The biopolymer sugarcane as filling material of critical defects in rats

PURPOSE: To evaluate the effects of particulate (granule-shaped) SCB on bone repair relating it to its biocompatibility and bone neoformation. METHODS: Thirty Wistar rats were submitted to a one 7-mm-diameter defect and divided equally into three experimental groups, with two different postoperative times of evaluation, 90 and 120 days. Each calvaria defect was filled up with clot (control group), particulated autogenous bone or granulated SCB. Five animals of each group were assessed at 90 and 120 days after surgery. In these two periods, histological and histometric analysis were obtained. RESULTS: The clot group showed a bone resorption trend while the autogenous bone group a bone repair trend. However in the SCB group, the critical defect filled up only with fibrous connective tissue and presented none bone neoformation. CONCLUSION : The sugarcane biopolymer when used in critical size defects was a biocompatible material and proved to be a good material to fill bone cavities, keeping them as uniform areas filled with soft tissue and avoiding the tissue shrinkage.

Piercing labial como corpo estranho / Lip piercing as a foreign body

O uso do piercing oral se tornou muito comum na última década. o uso disseminado desse adereço pode trazer consequências na região bucal, relacionadas à instalação e permanência deste. A presença de piercings como corpoestranho inserido nos tecidos orais é pouco relatada pela literatura. este artigo tem como objetivo realizar uma revisão da literatura sobre piercing bucal e relatar um caso adicional de piercing lábio como corpoestranho.

Oral piercing has become very common over the last ten years. The widespread use of piercing may have consequences in the oral region related to installation and maintenance. The presence of foreign body piercings inserted into the oral tissues is rarely reported in the literature. This article sets out to review the literature on oral piercing and report an additional case of lip piercing as a foreign body.

Osteossarcoma em Mandíbula - Relato de Caso / Osteosarcoma in the Mandible- Case report

O Osteossarcoma é uma neoplasia maligna agressiva, de origem mesenquimal, caracterizada por formação de osso irregular imaturo, produção de matriz osteoide e células fusiformes estromais malignas. É o tumor maligno primário mais comum do osso, responsavel por aproximadamente 20% dos sarcomas, sendo que 5% destes ocorrem nos maxilares. Os sintomas mais frequentes são o aumento de volume local, dor intensa e limitação funcional. Os fatores etiológicos estão associados às características do paciente (idade, sexo, raça, etnia, peso, altura) fatores genéticos e anomalias ósseas pre-existentes. O diagnóstico é obtido através de exames tomográficos e anatomopatológicos. O tratamento atual do osteossarcoma consiste em ressecção cirúrgica e quimioterapia complementar. O prognóstico desses pacientes melhorou nos últimos anos devido ao estadiamento adequado das lesões, acurados métodos de imagem e, principalmente, à poliquimioterapia. Este artigo descreve um caso de Osteossarcoma em indivíduo de 39 anos, gênero feminino, com grande lesão exofítica do corpo mandibular direito, assimetria facial e evolução de 3 meses. O diagnóstico foi estabelecido por achados clínicos, imaginológicos e histopatológicos. Conclui-se que é fundamental o tratamento cirúrgico precoce da lesão primária para minimizar seu comportamento recidivante e metastático.

Osteosarcoma is an aggressive malignancy of mesenchymal origin, characterized by irregular immature bone formation, osteoid matrix production and malignant spindle cell stroma. It is the most common primary malignant tumor of bone, accounting for approximately 20% of sarcomas, but only 5% of these occur in the jaw. The most common symptoms are local swelling, pain and functional limitation. The etiologic factors are associated with patient characteristics (age, sex, race, ethnicity, weight, height) genetic factors and pre-existing bone abnormalities. Diagnosis is obtained through CT scans and pathology. The current treatment for osteosarcoma consists of surgical resection and additional chemotherapy. The prognosis of these patients has improved in recent years due to proper staging of the lesions, accurate imaging methods and especially multidrug therapy. This article describes a case of Osteosarcoma in an individual of 39 years, female, with a large exophytic lesion of the right mandibular body, facial asymmetry and evolution of three months. The diagnosis was established by clinical, imaging and histopathology. We conclude that surgical treatment is crucial early primary lesion to minimize recurrent and metastatic behavior.