Search | Global Index Medicus

1.

Effects of cadmium treatment in vitro on the uptake and release of [3H]serotonin by human blood platelets.

Mukhopadhyay, S; Mukhopadhyay, S; Addya, S; Bhattacharya, D K; Chatterjee, G C.

Indian J Biochem Biophys ; 1989 Feb; 26(1): 56-60

Article in English | IMSEAR | ID: sea-27344

ABSTRACT

Effects of cadmium treatment on human platelets were studied with respect to uptake and release of 5-[3H]hydroxytryptamine (5-HT). The uptake of 5-[3H]HT in the presence of varying concentrations of CdCl2 (0.001-10 mM) was inhibited significantly with respect to control platelets and the inhibition was maximum at 1 mM CdCl2 concentration. From studies on the kinetics of 5-[3H]HT uptake a higher Km and significantly lower Vmax for CdCl2-treated platelets were observed. CdCl2 stimulated spontaneous release but inhibited thrombin-induced release of 5-[3H]HT. Spontaneous release of 5-[3H]HT induced by CdCl2 was not significantly altered in the presence of externally available CaCl2 (1 mM).

Subject(s)

Blood Platelets/drug effects , Cadmium/pharmacology , Humans , Serotonin/blood , Thrombin/pharmacology

2.

Studies on the antioxidant defence system and activation of human blood platelets under mercuric chloride treatment in vitro.

Mukhopadhyay, S; Mukhopadhyay, S; Addya, S; Bhattacharya, D K; Chatterjee, G C.

Indian J Biochem Biophys ; 1988 Oct; 25(5): 438-41

Article in English | IMSEAR | ID: sea-28442

Subject(s)

Antioxidants , Blood Platelets/drug effects , Humans , Malondialdehyde/metabolism , Mercuric Chloride/pharmacology

3.

Effect of methionine supplementation on lanthanum chloride and neodymium chloride induced alterations in enzymes of the antioxidant defence system and gamma-glutamyl cycle in chick liver.

Ghosh, N; Mukhopadhyay, S; Chattopadhyay, D; Das, M; Addya, S; Chatterjee, G C.

Indian J Biochem Biophys ; 1988 Aug; 25(4): 336-40

Article in English | IMSEAR | ID: sea-26817

Subject(s)

Animals , Catalase/metabolism , Chickens , Enzyme Activation/drug effects , Food, Fortified , Glutathione/metabolism , Glutathione Peroxidase/metabolism , Lanthanum/toxicity , Lipid Peroxides/biosynthesis , Liver/enzymology , Methionine/administration & dosage , Neodymium/toxicity , Oxidation-Reduction/drug effects , Sulfhydryl Compounds/biosynthesis

4.

Effects of acute oral administration of cadmium chloride on uptake of element and control of lipoperoxidative process in hepatic and renal nuclear fractions of rats.

Das, M; Ghosh, N; Chattopadhyay, D; Addya, S; Chatterjee, G C.

Indian J Exp Biol ; 1988 Jun; 26(6): 449-52

Article in English | IMSEAR | ID: sea-58282

Subject(s)

Administration, Oral , Animals , Cadmium/administration & dosage , Cadmium Chloride , Cell Nucleus/drug effects , Kidney/drug effects , Lipid Peroxidation/drug effects , Liver/drug effects , Male , Rats

5.

Interaction of lanthanum and calcium ions during uptake and release of serotonin by human blood platelets in vitro.

Mukhopadhyay, S; Mukhopadhyay, S; Addya, S; Chatterjee, G C; Bhattacharya, D K.

Indian J Biochem Biophys ; 1988 Jun; 25(3): 257-61

Article in English | IMSEAR | ID: sea-27196

Subject(s)

Blood Platelets/drug effects , Calcium Chloride/pharmacology , Humans , Lanthanum/pharmacology , Serotonin/blood

6.

Cellular defence mechanism under the influence of lanthanum intoxication in chick bone marrow.

Ghosh, N; Chattopadhyay, D; Mukhopadhyay, S; Addya, S; Chatterjee, G C.

Indian J Exp Biol ; 1988 May; 26(5): 374-6

Article in English | IMSEAR | ID: sea-62880

Subject(s)

Animals , Antioxidants/metabolism , Bone Marrow/drug effects , Chickens , Enzyme Activation/drug effects , Glutathione/metabolism , Glutathione Transferase/metabolism , Lanthanum/toxicity , Male , Malondialdehyde/biosynthesis , Oxidoreductases/metabolism

7.

Effect of cadmium administration on enzymes of intestinal epithelial cells in rats.

Chattopadhyay, D; Mukhopadhyay, S; Ghosh, N; Addya, S; Chatterjee, G C.

Indian J Biochem Biophys ; 1987 Aug; 24(4): 234-7

Article in English | IMSEAR | ID: sea-26637

Subject(s)

Animals , Cadmium/metabolism , Disaccharidases/metabolism , Glutathione/metabolism , Intestinal Mucosa/drug effects , Lipid Peroxides/metabolism , Male , Rats , Superoxide Dismutase/metabolism

8.

Effects of in vivo cadmium administration to rats on certain functional parameters of isolated erythrocytes.

Das, M; Mukhopadhyay, S; Addya, S; Chakravarti, K; Chatterjee, G C.

Indian J Exp Biol ; 1987 Apr; 25(4): 244-8

Article in English | IMSEAR | ID: sea-58445

Subject(s)

Animals , Cadmium/pharmacology , Cadmium Chloride , Cadmium Poisoning/blood , Cytochrome-B(5) Reductase/blood , Erythrocytes/drug effects , Glucosephosphate Dehydrogenase/blood , Glutathione/blood , Hemoglobins/metabolism , Male , Rats

9.

Antioxidant protection mechanism of chick bone marrow: effects of toxicant induced stress.

Ghosh, N; Addya, S; Mukhopadhyay, S; Chattopadhyay, D; Chatterjee, G C.

Indian J Exp Biol ; 1987 Apr; 25(4): 253-5

Article in English | IMSEAR | ID: sea-62350

Subject(s)

Animals , Bone Marrow/drug effects , Catalase/metabolism , Chickens , Glutathione/metabolism , Glutathione Peroxidase/metabolism , Glutathione Reductase/metabolism , Glutathione Transferase/metabolism , Lipid Peroxides/metabolism , Male , Neodymium/toxicity , Superoxide Dismutase/metabolism

10.

Effects of lead toxicity on liver and spleen ferritins in rats.

Santra, M; Basu, A; Ray, M K; Addya, S; Chatterjee, G C.

Indian J Biochem Biophys ; 1986 Oct; 23(5): 291-3

Article in English | IMSEAR | ID: sea-26977

Subject(s)

Animals , Ferritins/metabolism , Iron/metabolism , Lead Poisoning/metabolism , Liver/metabolism , Male , Organ Specificity , Organometallic Compounds/pharmacology , Rats , Spleen/metabolism

11.

Effects of mercuric chloride antioxidant defense components of rat erythrocyte and plasma: influence of vitamin E supplementation.

Addya, S; Chakravarti, K; Das, M; Ghosh, N; Chakravarti, D; Chatterjee, G C.

Indian J Exp Biol ; 1986 Jul; 24(7): 468-70

Article in English | IMSEAR | ID: sea-55772

Subject(s)

Animals , Antioxidants , Catalase/blood , Ceruloplasmin/blood , Erythrocytes/drug effects , Glutathione/blood , Glutathione Transferase/blood , Mercuric Chloride/toxicity , Rats , Superoxide Dismutase/blood , Vitamin E/pharmacology

12.

Antioxidant defence system of erythrocytes in relation to Agrobacterium tumefaciens lipopolysaccharide administration in mice.

Haldar, S; Basu, A; Chakraborty, K; Addya, S; Santra, M; Chatterjee, G C.

Indian J Exp Biol ; 1984 Mar; 22(3): 123-5

Article in English | IMSEAR | ID: sea-57723

Subject(s)

Animals , Catalase/blood , Cytochrome-B(5) Reductase/blood , Erythrocytes/enzymology , Glucosephosphate Dehydrogenase/blood , Glutathione/blood , Glutathione Peroxidase/blood , Glutathione Reductase/blood , Lipid Peroxides/blood , Lipopolysaccharides/pharmacology , Mice , Rhizobium , Superoxide Dismutase/blood

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