Clinical, Statistical and immunocytochemical characterization of giant cell tumour of bone among Egyptian population

Clinical and immunocytochemical analysis of twenty eight cases of giant cell tumour of bone was performed in this study. The results revealed that nine of the cases were benign, while the other nineteen were malignant. The female to male ratio was 2.5 : 1. The average age incidence was 28.18 years. The most common site of occurrence was the femur, anti endothelial antibody revealed negative immunocytochemical reaction of the stromal cells and giant cells for both benign and malignant cases; while using anti-HLA-DR antibody demonstrated positive immune reaction of some of the strumal and giant cells of all the cases examined