ABSTRACT
Objective of the present study was to investigate the antibacterial activity of Sea buckthorn [Hippophae rhamnoides L.] berries and leaves against methicillin resistant Staphylococcus aureus [MRSA] by using the standard disc diffusion method. Chloroform, n-hexane and aqueous extract of the plant parts were used. Doses of 2mg/ml, 4 mg/ml and 6mg/ml were tested against the microorganism, and the zone of inhibition was compared against the standard drug vancomycin. Results indicated that n-hexane and chloroform extracts of berries and n-hexane extract leaves showed significant [p<0.05] antibacterial activity comparable with vancomycin. It was concluded from the study that extracts berries and leaves of Hippophae rhamnoides have antibacterial activity against MRSA