ABSTRACT
Objective: To determine the frequency of malignancy in solitary nodule of thyroid
Study Design: Observational / Descriptive study
Place and Duration of Study: This study was conducted in the Department of Otolaryngology and Head and Neck Surgery at Civil Hospital Karachi from January 2007 to July 2008
Materials and Methods: This study comprises of 70 cases, in one and half years. We have included all cases of solitary nodule of either sex more than 10 years and excluded those patients who were exposed to radiation or underwent any sort of neck surgery previously. All Patients with solitary thyroid nodule were investigated with routine hematological and biochemical tests, thyroid profile, thyroid Scan, ultra sound neck and FNAC in outpatient department. At admission all risks/benefits of surgical procedures were explained to patients
Post-operative histopathological report of specimen was compared with preoperative fine needle aspiration cytology
Results: In our 70 cases study 59 patients were diagnosed with benign and 11 with malignant disease. Papillary carcinoma was found the most common tumor in 63.63%
Conclusion: Papillary carcinoma is the most common tumor in solitary thyroid nodule in our study followed by