ABSTRACT
This study aimed to determine whether the Full Outline of Unresponsiveness [FOUR] score is an accurate predictorof discharge outcome in traumatic brain injury [TBI] patients and to compare its performanceto Glasgow coma scale [GCS]. This is diagnostic study conducted prospectively on 53 TBI patients admitted to ICU of education hospitals of Medical Science University of Mazandaran during February 2013 to June 2013. Data collection was done with a checklist including biographic, clinical information and outcome. The FOUR score and GCS were determined by the researcher in the first 24 hours. Outcomes considered as in-hospital mortality and poor neurologic outcome [Glasgow Outcome Scale [GOS] 1-3] in discharge time from the hospital. In terms of predictive power for in-hospital mortality, the area under the receiver operating characteristic [ROC] curve was 0/92 [95% CI. 0/81-0/97] for FOUR score and 0/96 [95% CI. 0/87-0/99] for GCS. In terms of predictive power of poor neurologic outcome, the area under the ROC curve was 0/95 [95% CI. 0/86-0/99] for FOUR score and 0/90 [95% CI.0/79-0/96] for GCS as evidenced by GOS 1-3. The cut-off of 6 showed sensitivity and specificity of total four score predicting poor outcome at 0/86 and 0/87 while the cut-off of 4 showed the value of in hospital mortality at 0/90 and 0/90. The total GCS score showed sensitivity and specificity 0/100 and 0/61 at cut-off 7 in predicting poor outcome while in predicting mortality at cut-off of 4 this range was 0/100 and 0/92. The FOUR score is an accurate predictor of discharge outcome in TBI patients. Thus, researchers recommend for therapeutic Schematizationto use in neurosurgical patients at admission day.