ABSTRACT
COVID-19 infection is an inflammatory state and has varied presentation ranging from mild to severe condition. The second wave of COVID-19 resulted in greater mortality and morbidity as compared to first wave both in general as well as in pregnant patient. As the progression of disease is rapid and fatal hence there is a need of reviewing relevant inflammatory markers for predicting the disease course and severity. The inflammatory markers considered are Interleukins, CRP, LDH, serum Ferritin, Neutrophil/ lymphocyte ratio and in some cases serum Procalcitonin. These markers are raised in other inflammatory conditions also and therefore the maximum predictability of various markers differs in different conditions. COVID-19 in pregnancy in itself is challenging as it alters the immunity and hemodynamic and therefore the value of these markers in pregnancy can affect the sensitivity and specificity in predicting the severity of the disease. This review will evaluate the role of inflammatory markers in general population as well as pregnancy with regards to their prognostication in assessing the disease severity.
ABSTRACT
Dermatosis of pregnancy encompasses a group of skin conditions that occurs due to interaction of multiple factors in the body during pregnancy or during post-partum period. We presented a case of 25-year-old G4P1L1A2 with initial symptom of urticarial rash which later progressed to a rare and a scary dermatosis of pregnancy which became a challenge both to the obstetrician and the dermatologist.
ABSTRACT
Background: The aim of this study is to evaluate the maternal and perinatal outcome in term primigravida with isolated oligohydramnios.Methods: A retrospective, case–control study was carried out in the department of OBG, School of Medical Sciences and Research, Sharda Hospital, Greater Noida from November 2014 to October 2017. The study population comprised of low-risk primigravida with singleton, term pregnancy, with vertex presentation and intact membranes. After meeting the inclusion and exclusion criterion, the study population was divided into cases (n = 51) and control group (176) and the results were analyzed in reference to rate of induction of labour, C. Section rate and the perinatal outcome.Results: Isolated oligohydramnios is associated with increased rate of induction of labour and increased operative interference, but perinatal outcome in terms of mean birth weight, Apgar score at 5 min and NICU admissions for over 24 hours, are not statistically significant in comparison with control group.Conclusions: Isolated oligohydramnios is not an indicator of adverse perinatal outcome.