ABSTRACT
This study was conducted to determine the pattern of cutaneous malignancies among patients attending the skin out-patient department Hayatabad Medical Complex Peshawar. This was descriptive analysis of skin cancers carried from January 2011 to December 2011. Histologically diagnosed skin cancers were reviewed and analyzed according to age, gender, site of distribution and histological types. Hundred histologically diagnosed skin malignancies were reported during the period under review. Sixty cases [60%] were males and 40 cases [40%] females with a male to female ratio of 1.5:1. Age ranged from 22 years to 86 years. Mean age was 57.05 +/- 11.39 SD. Mean duration of disease in months were 16.78 +/- 9.07SD. Basal cell carcinoma [BCC] was the most common malignancy consisting of 32[32%] cases followed by Squamous cell carcinoma [SCC 18%] with 10 [10%] cases of melanoma and 9[9%] cases of Mycosis Fungoides. Actinic Keratosis, Kaposi's sarcoma, Bowen's disease, Dermatofibroma, Atypical fibroxanthoma constituted the remaining. The most common skin malignancy was BCC followed by SCC and melanoma. Larger studies should be conducted to ascertain the actual prevalence of skin tumors
ABSTRACT
The aim of the study was to evaluate the diagnostic performance of fine needle aspiration cytology in the diagnosis of breast lumps. All patients who underwent FNA breast lumps at Rehman Medical Institute, Peshawar during 2006 to 2008 were included in this descriptive crosssectional study. The FNA procedure was performed and interpreted by experienced cyto-pathologists. FNAC of 102 breast lumps were analysed. The age range of the patients was 15-80 years [mean 38.11 years]. Inadequate cases were 2.94%, malignant 30.39%, atypical/suspicious of malignancy 6.86%, and benign 59.80%. Malignant lesions predominated in the 5[th] and 6[th] and benign in the 3[rd] and 4[th] decades of life. FNAC of breast is simple, cost-effective and less traumatic method for diagnosis of breast lumps. Combined with physical examination and imaging studies, it is a highly sensitive diagnostic tool and can reduce the need for open biopsy
ABSTRACT
Acanthosis nigricans [AN] is characterized by velvety, hyperpigmented, verrucous, symmetric and occasionally pruritic plaques along with papillomatous lesions which have a special predilection for neck, axillae, groin, umbilicus and mucosal regions. Rarely, it presents as a paraneoplastic syndrome and prompts a thorough search for an internal malignancy. We present here a case of malignant acanthosis nigricans seen in an elderly patient who was found to have underlying adenocarcinoma of the lower end of esophagus. After diagnosing associated malignancy, he was referred for further evaluation and subsequent surgical resection of tumour
Subject(s)
Humans , Male , Middle Aged , Paraneoplastic Syndromes , Early Detection of Cancer , Adenocarcinoma/diagnosis , Esophageal NeoplasmsABSTRACT
A rare case of obstructive Jaundice in a 35 yrs old male from Afghanistan is presented with recurring attacks of upper abdominal pain and jaundice. Ultrasound examination revealed multiple gallstones with' dilated common bile duct. During exploration of common bile duct, five leaf like liver flukes [Fasciola Hepatica] were recovered and identified. Patient was treated with Albendazole and had an uneventful recovery. Biliary fascioliasis should be considered in the differential diagnosis of obstructive jaundice