ABSTRACT
A rare case of inflammatory pseudotumour of liver in a child is reported. The child presented with obstructive jaundice and was considered to have malignant tumour of liver clinically and by imaging modalities. Resection of left hepatic lobe with the mass was done. Histologically, the lesion consisted of an admixture of proliferation of lymphocytes, plasma cells and fibroblasts along with vasculitis and variable amount of hyaline fibrosis. Adjacent liver showed evidence of biliary cirrhosis and multiple microabscesses. Many of the previously reported cases were also diagnosed clinically and radiologically to be malignant tumours of liver. The case is reported to create awareness of this rare entity.
Subject(s)
Child , Diagnosis, Differential , Female , Granuloma, Plasma Cell/diagnosis , Humans , Liver Diseases/diagnosis , Liver Neoplasms/diagnosisSubject(s)
Adult , Female , Humans , Male , Middle Aged , Neoplasms/blood , Biomarkers, Tumor/blood , alpha 1-Antitrypsin/analysisABSTRACT
Arterial pattern of hands and feet-vessels was studied in 26 patients of leprosy by percutaneous arteriography, and in these cases muscle biopsy was also done. The vessels in leprosy were showing smooth tapering, absence of collaterals, occlusion of the artery and rippling (tortousity) of vessels. Such abnormal pictures were seen in all the arteriograms studied, and in 82% of of cases moderate to severe vascular changes were seen. Decreased blood flow through the arteries in the distal part of the limb leading to ischaemia, is probably the cause for deformity and/or ulceration in the leprosy. Presence of vascular thickening, perivascular granuloma and lymphocytic infiltration in the muscle may be possible explanation for angiographic findings and is felt to be related to trophic ulceration.