ABSTRACT
The purpose of this study was to look at the serum levels of Visfatinin non-obese ordinary circulatory strain, non-obese hypertension and obesity hypertension. Research plan was Comparative cross sectional study. The Place and span was collaborating with the Institute of Medical Science in Lahore at the Graduate School of Medicine Laboratory of Lahore. This research included 81 subjects, each separated into 3 gatherings: non-obese normotensive, non-obese hypertensive and obesity hypertension. Circulatory strain level, BMI (Body Mass Index) and WHR (Waist to Hip Ratio) were estimated. Fasting blood tests were gathered to evaluate Visfatin levels in the serum. The results showed that the Mean serum Visfatin levels of 70.97 ± 50.30 ng/ml were seen in obese hypertensive patients contrasted with 33.71 ± 10.66 ng/ml and 5.21 ± 3.57 ng/ml for non-obese hypertensive and non-obese ordinary circulatory strain. It is concluded that Serum Visfatin levels can be utilized as biomarkers for assessing hypertension in obese and non-obese patients.
ABSTRACT
Marginal gingival recession can cause major functional and esthetic problems. Advanced flaps are the simplest, yet unpredictable procedures for managing these conditions. The predictability of root coverage can be increased by combining coronally advanced flap (CAF) or its modified approach with other regenerative techniques. Objective: To ascertain the potential benefits of platelet-rich fibrin (PRF) on modified CAF for the treatment of gingival recession. Materials and Methods: Study comprised of 12 patients with Millers' class I and class II gingival recession in two non-adjacent anterior teeth having a minimum 3 mm width of attached gingiva. Following split-mouth design, one tooth with gingival recession was subjected to modified CAF, while another was treated by CAF with PRF. The clinical parameters, i.e., plaque index, modified sulcular bleeding index, vertical gingival recession depth (VGRD), gingival recession width (GRW), clinical attachment level (CAL), and gingival thickness (GT) were recorded at baseline, 1 month, 3 months, and 6 months. Results: VGRD, GRW, CAL, and GT improved significantly from baseline to 1 month in both test and control groups. However, change in these parameters from 1 month to 3 months and 3 months to 6 months were statistically nonsignificant in both groups. On intergroup comparison, only the change in GT was found to be statistically significant (P < 0.05) at all three post-treatment visits. Conclusion: Benefits of the combined technique in terms of increased GT appear to justify the use of PRF along with modified CAF for the treatment of mild to moderate gingival recessions.