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ABSTRACT Background: Hemorrhagic transformation (HT) is a complication in ischemic strokes, regardless of use of reperfusion therapy (RT). There are many predictive scores for estimating the risk of HT. However, most of them include patients also treated with RT. Therefore, this may lead to a misinterpretation of the risk of HT in patients who did not undergo RT. Objective: We aimed to review published predictive scores and analyze their accuracy in our dataset. Methods: We analyzed the accuracy of seven scales. Our dataset was derived from a cohort of 1,565 consecutive patients from 2015 to 2017 who were admitted to a comprehensive stroke center. All patients were evaluated with follow-up neuroimaging within seven days. Comparison of area under the curve (AUC) was performed on each scale, to analyze differences between patients treated with recombinant tissue plasminogen activator (tPA) and those without this treatment. Results: Our dataset provided enough data to assess seven scales, among which six were used among patients with and without tPA treatment. HAT (AUC 0.76), HTI (0.73) and SEDAN (0.70) were the most accurate scores for patients not treated with tPA. SPAN-100 (0.55) had the worst accuracy in both groups. Three of these scores had different cutoffs between study groups. Conclusions: The predictive scores had moderate to fair accuracy for predicting HT in patients treated with tPA. Three scales were more accurate for predicting HT in patients not treated with tPA. Through standardizing these characteristics and including more patients not treated with RT in a large multicenter series, accurate predictive scores may be created.
RESUMO Background: Transformação hemorrágica (TH) é uma complicação frequente no acidente vascular cerebral (AVC) isquêmico independente do uso de terapia de reperfusão (TR). Diversos escores preditivos de TH foram elaborados. Entretanto, a maioria desses escores incluíram pacientes submetidos a TR — o que pode levar à má interpretação do risco de TH nos pacientes não submetidos a TR. Objetivo: Nosso objetivo é revisar escores preditivos já publicados e analisar a sua acurácia em nossa amostra. Métodos: Analisamos a acurácia de sete escores. Nosso banco foi criado de uma coorte de 1.565 pacientes consecutivos, admitidos entre 2015 e 2017 em um centro avançado de AVC. Os pacientes realizaram neuroimagem de controle em até sete dias. Uma comparação entre áreas abaixo da curva/característica de operação do receptor (AUC) foi realizada, analisando-se as diferenças entre grupos de pacientes tratados ou não com ativador de plasminogênio tecidual recombinante (tPA). Resultados: Nosso banco de dados proporcionou informação suficiente para avaliar sete escores, dos quais seis foram aplicados em pacientes tratados ou não com tPA. HAT (AUC 0,76), HTI (0,73) e SEDAN (0,70) foram os escores mais acurados em pacientes não tratados com tPA. SPAN-100 (0,55) teve a pior acurácia nos grupos. Três desses escores apresentaram diferentes valores de corte entre os grupos. Conclusões: Os escores apresentaram de boa a moderada acurácia na predição de TH em pacientes tratados com tPA. Três escores foram mais acurados em pacientes não tratados com tPA. A parametrização dessas características e a inclusão de mais pacientes não tratados com TR em um estudo multicêntrico poderia levar a escores mais acurados.
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ABSTRACT Three parasitoid species Aphidius colemani, Aphidius matricariae (Hymenoptera: Braconidae) and Aphelinus abdominalis (Hymenoptera: Aphelinidae) were evaluated concerning their parasitism potential in two aphid species, Aphis glycines and Aphis gossypii (Hemiptera: Aphididae). The feeding of these two aphid species, even at low sums, can significantly damage photosynthesis and is found to transmit many kinds of plant viruses, which impact potential adverse effects on the plants. The overall parasitization on all nymphal ages in As. glycines was accomplished by Ad. colemani (60.50%), Ad. matricariae (49.16%) and Al. abdominalis (40%), while in As. gossypii parasitism exhibited by Ad. colemani (79.48%), Ad. matricariae (65.33%) and Al. abdominalis (58.83%). Aphelinus abdominalis exhibited the lowest parasitism in both given species as hosts. Significant differences in parasitism of different parasitoids and host species were observed. Concerning the preference of nymphal instars, we found that parasitoids species prefer to parasitize 1st- 4th instars in As. gossypii while in As. glycines 2nd, 1st, 3rd and 4th. Our results showed that the parasitism increases with the increase of parasitoid numbers and hosts densities.
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SUMMARY: Accurate implant sizing is one of the major determinants in defining the success of total knee arthroplasty (TKA). Current TKA implants are based on Caucasian knee morphometry which is well documented to be larger than Asian knees. Even more, with regards to sizing, implant mismatch tends to be more evident in the female population. This study was designed to evaluate the distal femur dimensions of Malaysian female patients who underwent TKA in our institution and to compare them with the current prosthetic system in use. A total of 199 female patients (207 knees) who underwent TKA were enrolled in this study. Intraoperatively, the AP dimensions (medial and lateral condyles) and mediolateral (ML) width were measured. Known dimension of the femoral component of the prosthetic knee system currently in use were compared with the morphological data. The average femoral component overhang was 2.11 mm (SD 3.94 mm). There was significant difference between the mean ML width of the resected femur and the femoral component (p<0.01). Analysis also revealed a significant positive and weak relationship between both, AP (medial and lateral) and ML dimension. The aspect ratio (ML/AP) of the native femur was generally smaller than the implant aspect ratio which is likely to cause overhang in our population. In general, this study shows that the knees of our female sub-population are even narrower than the other Asian female knees from previous studies. Implants should be designed based on the morphological data of the local population. Implant manufactures should tailor them to accommodate a smaller change in ML width for an increment in the AP length and provide several ML widths for one AP length to obtain a better fitting prosthesis hence curbing the problem of ML overhang.
RESUMEN: El tamaño exacto del implante es uno de los principales determinantes para definir el éxito de la artroplastía total de rodilla (ATR). Los implantes de TKA se basan en la morfometría de rodilla caucásica, cuyo tamaño está reportado como mayor que las rodillas asiáticas. Más aún, en lo que respecta al tamaño, el desajuste de los implantes tiende a ser más evidente en la población femenina. Este estudio fue diseñado para evaluar las dimensiones del fémur distal de pacientes mujeres malasias que se sometieron a ATR en nuestra institución y compararlas con el sistema protésico actual. En este estudio se incluyeron un total de 199 pacientes (207 rodillas) que se sometieron a ATR. Intraoperatoriamente, se midieron las dimensiones AP (cóndilos medial y lateral) y el ancho mediolateral (ML). Se comparó la dimensión conocida del componente femoral del sistema protésico de rodilla actualmente en uso con los datos morfológicos. El voladizo o sobresaliencia del componente femoral fue de 2,11 mm (DE 3,94 mm). Hubo una diferencia significativa entre el ancho ML medio del fémur resecado y el componente femoral (p <0,01). El análisis también reveló una relación significativa positiva y débil entre las dimensiones AP (medial y lateral) y ML. La relación de aspecto (ML / AP) del fémur nativo fue más pequeña que la relación de aspecto del implante, lo que probablemente cause un voladizo en nuestra población. En general, este estudio muestra que las rodillas de nuestra subpoblación femenina son incluso más estrechas que otras rodillas de mujeres asiáticas reportadas en estudios anteriores. Los implantes deben ser diseñados en base a los datos morfológicos de la población local. Los fabricantes de implantes deben adaptarlos a un cambio más pequeño en el ancho de ML para un incremento en la longitud AP y proporcionar varios anchos ML para una longitud AP con el objetivo de obtener una prótesis de mejor ajuste y frenar el problema del voladizo ML.
Subject(s)
Humans , Female , Prostheses and Implants , Arthroplasty, Replacement, Knee , Femur/anatomy & histology , Knee/anatomy & histology , Cross-Sectional Studies , Intraoperative Period , MalaysiaABSTRACT
Dental students commonly face the problem of overhanging proximal margins and unsatisfactory proximal contact points (PCPs) while restoring Class II cavities in posterior teeth. Various matrix band systems are used in dental clinics to avoid such problems. Aims: The aim of this study is to compare the effects of two matrix band systems, circumferential matrix system and sectional matrix system on the PCPs and contours when restoring Class II cavities in posterior teeth. Settings and Design: This was a randomized controlled clinical trial done at College of Dentistry, Qassim University, Saudi Arabia. Subjects and Methods: Total 1200 Class II cavities in teeth were selected for this study. Treatment was done by senior undergraduate students. Cavities were randomly divided into two groups. Group 1: Total 600 cavities were restored using circumferential band system. Group 2: Total 600 cavities were restored using sectional band system. Teeth were restored either with the composite or the amalgam restoration. Contact points were evaluated. The presence or absence of proximal overhangs was assessed. Overhanging margins were categorized as positive overhangs, negative overhangs, and absent overhangs. Statistical Analysis Used: To identify the relationship between matrix band systems and other factors, Chi-square tests (χ2-tests) and Z-tests were used. Pearson correlation coefficient was computed and logistic regression analysis was carried out to assess variables that can affect proximal margins and contact points of final restorations. Results: All optimum contacts 389 (100%) were found in restorations done using sectional band system. A highly significant association was found between open contact points and negative overhanging margins with the use of circumferential matrix band system (P < 0.00). Conclusion: Sectional matrix band system has been found superior to circumferential matrix band system.
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Due to inconsistency in demand and supply of fishmeal there is immense need of alternate protein sources. Present project was therefore designed to replace costly fishmeal (FM) with low-priced fermented fish silage (FFS) in fish feed. Fermented fish silage was prepared by fermentation process using Lacto bacillus bacteria and its fatty acid profile and effect on digestive system of Labeo rohita was investigated. Lipid contents were isolated by Soxhlet apparatus and recorded as 6.23 ± 1.23 g/100g of fermented fish silage (FFS). Fatty acid profile of extracted Lipids was determined by gas liquid chromatography (GLC), sufficient amount of unsaturated fatty acids were found with pattern mono unsaturated fatty acids (MUFA) > saturated fatty acids (SFA) >poly unsaturated fatty acids (PUFA). Three treatment diets containing 100% silage (T1), 75% silage (T2) and 50% silage (T3) were prepared by mixing it with soybean meal (SBM) and rice bran as co-ingredients while fermented fish silage was replaced by fishmeal in control diet (T0). The experiment was conducted in glass aquaria in triplicate. Fish growth parameters were recorded fortnightly while physicochemical parameters of water were recorded on daily basis. After completion of feeding trial, three fish were randomly dissected to excise out their intestines and determine activity for protease, amylase and lipase enzymes. Non-significant differences (P<0.05) were recorded in growth parameters and enzymatic activity among all diets except lipase enzyme. Deceptively, it can be concluded that FFS has reasonable concentration of nutrients and unsaturated fatty acids so it can successfully replace fishmeal in fish diets.
Devido à diferença na procura e na oferta de farinha de peixe há imensa necessidade de qualquer membro suplente da fonte de proteína. Tão presente projeto foi projetada para substituir a dispendiosa farinha de peixe (FM) com barato peixe fermentado de ensilagem (FFS) em alimentos para peixes. FFS foi preparado pelo processo de fermentação usando Lactobacillus bactérias e seu perfil de ácidos graxos e efeito sobre o sistema digestivo de Labeo rohita foi investigado. Conteúdo lipídico foram isoladas pelo aparelho de Soxhlet e registadas como 6,23 ± 1,23 g/100g de FFS. Perfil de ácidos graxos extraídos de lipídios foi determinada por cromatografia líquida de gás (GLC). Quantidade suficiente de ácidos graxos insaturados foram encontrados com padrão MUFA > SFA > AGPI. Tratamento de três dietas contendo silagem de 100% (T1), 75% silagem (T2) e 50% silagem (T3) foram preparados misturando com farinha de soja (SBM) e farelo de arroz como co ingredientes enquanto FFS foi substituído pela FM na dieta controle (T0). O experimento foi conduzido em aquários de vidro em triplicado. O Crescimento dos peixes foram anotados os parâmetros quinzenal enquanto parâmetros físico-químicos de água foram registradas diariamente. Após a conclusão do teste de alimentação, três peixes foram aleatoriamente dissecada a impostos especiais de consumo os seus intestinos e determinar a atividade de protease, enzimas amilase e lipase. As variações não significativas (P<0,05) foi registrada em parâmetros de crescimento e atividade enzimática entre as dietas exceto enzima lipase mostrou diferença significativa entre as dietas de tratamento. Aparentemente, é possível concluir que a concentração razoável de FFS tem nutrientes e ácidos graxos insaturados de modo que ela possa substituir com êxito a farinha de peixe na dieta de peixes.
Subject(s)
Fatty Acids , Fish Flour , Fishes , AmylasesABSTRACT
Background: The study was conducted to assess the awareness regarding Knowledge, Attitude and Practices about HIV/AIDS in the community of Rawalpindi and Islamabad. Methods: The study was conducted in Rawalpindi and Islamabad with age of 18 years and more. The data was randomly selected from 120 people having qualification of undermatric/matric/graduation/masters and above through questionnaire. The duration of the study was one year from April 2012 to March 2013. Results: Study showed that media is major source of awareness through Television (81.7%) and News Paper (67.5%).It was seen that 48.3% knew the difference between HIV and AIDS. 53.3% knew the signs and symptoms of HIV/AIDS but more than 46% did not know clinical features. Most of the community (79.2%) knew about the mode of transmission but small percentage (20.8%) did not have knowledge about transmission of disease. 85.8% knew about mode of prevention of HIV/AIDS. More than 80% of the participants suggested for compulsory screening of HIV/AIDS whereas a small percentage (up to 20%) did not suggest. Attitude of community was mix reply with positive attitude (58.3%) and negative attitude (41.7%).About 40% were in favor of health insurance whereas around 60% feel no need of health insurance to the HIV/AIDS patients.70% of the participants recommended to maintain the confidentiality of patient while 30% gave negative reply. Community was opinion that health awareness would reduce (96.7%) the risk of disease while only a small percentage (3.3%) thought for having no impact on prevention. Conclusions: The study showed sufficient knowledge and awareness but negative attitude of community towards patients of HIV/AIDS.
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Diabetes mellitus is the most common human disease and there is growing interest for plant based therapy in managing diabetes mellitus specifically in the developing world. In the present study, Rhazya stricta Decne extract was analysed for its antidiabetic activities. Crude methanolic extracts of different plant parts were tested in vivo on albino mice Balb-C, for the reduction of blood glucose, urea, cholesterol, triacylglycerides and glycosylated haemoglobin. Results obtained showed that leaves of R. stricta have best antidiabetic effect by reducing blood glucose level, Glycosylated haemoglobin, triacylglycerides and Cholesterol in hypergly-caemic mice. The R. stricta leaves extract being most active was further fractionated by solvent extraction using n- Hexane, ethyl acetate, chloroform and water and all fractions were tested for same activities. It was found that ethyl acetate fraction is most effective in the reduction of blood glucose level at fasting and random conditions and blood glucose reduction was comparable to Glucophage, a standard antidiabetic drug. The present study suggests that Rhazya stricta leaves extract and its ethyl acetate fraction has great potential for development of antidiabetic drug.
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Aims: The aim of this study was to investigate the antimicrobial activity of Terfezia claveryi crude extract on induced corneal ulcer in rabbit’s eye. Study Design: Study was carried out in Rabbits eye. Place and Duration of the Study: This study was conducted in the experimental laboratories at College of Applied Medical Sciences of Qassim University during the period from March to June 2013. Methodology: Crude aqueous extract of this truffle, in different concentrations, was introduced through intraperitoneal injection to rabbits for their safety dose. Corneal epithelial wound was induced in different groups of rabbit’s eye with sodium hydroxide and later this wound was contaminated with some selected bacteria like Staphylococcus aureus and Escherchia coli to produce iatrogenic infection. The healing power of different concentrations of T. claveryi crude extract was observed by different clinical findings. Results: We observed that 1.5% crude extract of this desert truffle significantly healed the corneal ulcer almost within 9 days. Delayed response in healing was observed with 3% T. claveryi, while 5% extract developed some extra corneal complications. The healing response of corneal ulcer to topical application of different concentrations of T. claveryi extract was compared with a synthetic antibiotic (Vigamox 0.5%) as a reference standard drug. Conclusion: It was concluded that aqueous extract of T. claveryi has no significant toxic effects against liver and kidney function parameters. The antibacterial activity of this desert truffle recommends as an alternative medicine for some corneal infections. However, the therapeutic role of some specific ingredients present in this truffle needs further investigations.
ABSTRACT
Diabetes mellitus is the most common human disease and there is growing interest for plant based therapy in managing diabetes mellitus specifically in the developing world. In the present study, Rhazya stricta Decne extract was analysed for its antidiabetic activities. Crude methanolic extracts of different plant parts were tested in vivo on albino mice Balb-C, for the reduction of blood glucose, urea, cholesterol, triacylglycerides and glycosylated haemoglobin. Results obtained showed that leaves of R. stricta have best antidiabetic effect by reducing blood glucose level, Glycosylated haemoglobin, triacylglycerides and Cholesterol in hypergly-caemic mice. The R. stricta leaves extract being most active was further fractionated by solvent extraction using n- Hexane, ethyl acetate, chloroform and water and all fractions were tested for same activities. It was found that ethyl acetate fraction is most effective in the reduction of blood glucose level at fasting and random conditions and blood glucose reduction was comparable to Glucophage, a standard antidiabetic drug. The present study suggests that Rhazya stricta leaves extract and its ethyl acetate fraction has great potential for development of antidiabetic drug.
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Pimpinella anisum L. (Aniseed) is mostly used as an immune stimulant, growth promoter, antifungal, antibacterial in many countries for centuries. The aim of this study was to determine the immunomodulatory effect of aniseed against Newcastle Disease (ND) and infectious bursal disease (IBD) viruses. The immunomodulatory effect of aniseed against ND and IBD viruses were determined by modifying splenic cell migration inhibition assay and differential leukocyte count for cellular immunity. Haemagglutination inhibition and indirect haemagglutination were used for measurement of humoral immune response against ND and IBD viruses, respectively. The present study suggests that the aniseed addition to basal diet at the rate of 0.5 g/kg and 1 g/kg of feed had best immunomodulatory activity both for humoral and cellular immune responses. However, at higher doses aniseed had adverse effects. Aniseed possesses significant immunomodulatory activity when it is added at lower doses i.e., 0.5 g/kg and 1 g/kg.
Pimpinella anisum L. (Anís) se utiliza principalmente como un estimulante inmunológico, promotor del crecimiento, antifúngico, y antibacteriano, en muchos países durante siglos. El objetivo de este estudio fue determinar el efecto inmunomodulador de anís contra la enfermedad de Newcastle (ND) y la enfermedad de la bursitis infecciosa (IBD). El efecto inmunomodulador de anís contra los virus ND y e IBD se determinaron mediante la modificación del ensayo de inhibición de la migración de células del bazo y recuento diferencial de leucocitos de la inmunidad celular. La inhibición de la hemaglutinación y hemaglutinación indirecta se utilizaron para la medición de la respuesta inmune humoral contra el virus de ND e IBD, respectivamente. El presente estudio sugiere que la adición de anís a la dieta basal a la tasa de 0,5 g/kg y 1 g/kg de alimentación tuvo una mejor actividad inmunomoduladora tanto para las respuestas inmunes humorales como celulares. Sin embargo, a dosis más altas de anís tuvo efectos adversos. El anís posee una importante actividad inmunomoduladora cuando se añade en dosis más bajas, es decir, 0,5 g/kg y 1 g/kg.
Subject(s)
Animals , Immunologic Factors/pharmacology , Pimpinella/chemistry , Seeds/chemistry , Infectious bursal disease virus , Newcastle disease virus , Bursitis/prevention & control , Chickens , Newcastle Disease/prevention & controlABSTRACT
The present study was conducted to evaluate growth promoting effect of Pimpinella anisum L. (aniseed) in broiler chickens in terms of body weight gain, organ weights, feed intake and feed conversion ratio (FCR). For this purpose, four levels (0.5, 1.0, 1.5 and 2.0 grams per kg feed) of aniseed powder were administered in feed from day 0 till the end of experiment (42 days of age). The body weight gain, feed intake and FCR were recorded on weekly basis. The birds showed good performance (better weight gain, better feed intake and FCR) when aniseed was fed in lower doses however, birds showed poor performance at higher levels of aniseed. Likewise, almost same pattern was observed for organ weights. This study suggests the good effect of aniseed on performance of broiler chickens at lower doses which suggests the further need of series experiments to find out the minimum safe levels of aniseed to be incorporated in broiler ration to get desirable results.
Se realizó el presente estudio para evaluar el efecto promotor del crecimiento de Pimpinella anisum L. (anís) en pollos de engorde en términos de ganancia de peso corporal, peso de los órganos, el consumo de alimento y conversión alimenticia (FCR). Para este propósito, cuatro niveles (0,5, 1,0, 1,5 y 2,0 gramos por kg de alimento) de anís en polvo se administraron en el pienso desde el día 0 hasta el final del experimento (42 días de edad). La ganancia de peso corporal, consumo de alimento y FCR fueron registrados en forma semanal. Las aves mostraron un buen rendimiento (mejor ganancia de peso, un mejor consumo de alimento y FCR) cuando el anís se alimentó en dosis más bajas, sin embargo, las aves mostraron malos resultados en los niveles más altos de anís. Del mismo modo, se observó casi el mismo patrón de peso de los órganos. Este estudio sugiere que el buen efecto del anís en el rendimiento de pollos de engorde en dosis más bajas que sugiere la necesidad adicional de experimentos de la serie para conocer los niveles de seguridad mínimos de anís que se incorporarán en la ración de pollos de engorde para obtener los resultados deseados.
Subject(s)
Animals , Animal Feed , Plant Extracts/administration & dosage , Pimpinella/chemistry , Chickens/growth & development , Seeds/chemistry , Animal Husbandry , Animal Nutritional Physiological Phenomena , Body Weight , Eating , Organ Size , PowdersABSTRACT
Major lower limb nerve blocks are relatively safe techniques. However, their efficacy for hip hemiarthroplasty is unknown. The objective of this study was to determine the effectiveness of combined femoral, sciatic, obturator and lateral femoral cutaneous [LFC] nerve blocks in providing adequate anesthesia for hip hemiarthroplasty. A total of 20 patients with fracture neck femur; who underwent hip hemiarthroplasty, participated in this observational study. In the induction room, all patients received ultrasound-guided femoral, proximal obturator, LFC and parasacral sciatic nerve blocks in addition to local infiltration at the proximal site of the skin incision. Anesthesia was considered to be adequate only if the surgery was completed without any requirement for opioid administration. All patients [100% [95% confidence interval, 86-100%]] had adequate anesthesia. Seventeen patients [85% [95% confidence interval, 63-96%] had mild discomfort during the reduction of the prosthetic femur head back into the hip socket; however, no supplementary analgesics were required. The combined femoral, sciatic, obturator and LFC nerve blocks in addition to local infiltration at the proximal site of skin incision could provide adequate anesthesia for hip hemiarthroplasty. Light sedation before reduction of the prosthetic femur head back into the hip socket is advisable
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The effect of pre-sowing magnetic treatments was investigated on germination, growth and yield of okra (Abelmoschus esculentus cv. Sapz pari). The dry okra seeds were exposed to sinusoidal magnetic field induced by an electromagnet. The average magnetic field exposure was 99 mT for 3 and 11 min and seeds with no magnetic field treatment were considered as control. Both treated and non-treated seeds were sown in experimental plots (120 m2) under similar conditions. Samples were collected at regular intervals for statistical analysis. A significant increase (P<0.05) was observed in germination percentage, number of flowers per plant, leaf area (cm2), plant height (cm) at maturity, number of fruits per plant, pod mass per plant and number of seeds per plant. The 99 mT for 11 min exposure showed better results as compared to control.
Subject(s)
Abelmoschus/growth & development , Abelmoschus/radiation effects , Germination/radiation effects , Magnetic Fields , Seedlings/growth & development , Seedlings/radiation effects , Seeds/growth & development , Seeds/radiation effectsABSTRACT
Acinetobacter baumannii causes infections of respiratory, urinary tract, blood stream and surgical sites. Its clinical significance has increased due to its rapidly developing resistance to major groups of antibiotics used for its treatment. There is limited data available on antimicrobial susceptibility of A.baumannii from Saudi Arabia. To determine the patterns of drug resistance of Acinetobacter baumannii and predisposing factors for its acquisition. In this descriptive study, 72 hospitalized patients infected with A.baumannii were studied. The clinical and demographic data of the patients were collected using a predesigned questionnaire. Isolation and identification of A.baumannii from all clinical specimens were done using standard microbiological methods. Antibiotic susceptibility testing was performed by disk diffusion method recommended by Clinical Laboratory Standards Institute. Majority of the isolates [61.1%] were from respiratory tract infections. A.baumannii isolates showed high drug resistance to piperacillin [93.1%], aztreonam [80.5%], ticarcillin, ampicillin, and tetracycline [76.4%, each] and cefotaxime [75%]. Only amikacin showed low rate of resistance compared to other antibiotics [40.3%]. About 36% patients had some underlying diseases with diabetes mellitus [11%] being the predominant underlying disease. High antimicrobial resistance to commonly used antibiotics was seen against A.baumannii isolates. Only amikacin was most effective against it
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It is retrospective and hospital based case control study which was conducted in the federal city of Islamabad in Pakistan in order to assess the risk factors of the urinary bladder cancer. This study was based on the 100 controls and 50 cases comprising 150 subjects which were selected for interview from the two hospitals and required information like gender, age, smoking habits, family history of cancer, etc., was achieved. Both the descriptive and analytical approaches were used to find out the dominating risk factors of the disease. Odds ratios and 95 % Confidence Intervals were obtained for analytical purpose by using the binary logistic regression model. Three factors including cigarette smoking, source of drinking water and fried items were found to be significant having odds ratios and 95% confidence intervals of (17.158, 6.244- 47.147), (0.192, 0.061- 0.603) and (12.206, 3.291- 45.275), respectively. The study revealed that cigarette smoking, consumption of tap water and high use of fried items increases the risk of developing bladder cancer. On the other hand, the use of government provided for drinking purpose is a protection against the urinary bladder cancer as compared to tap water.
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Presence of heavy metals in the aquatic systems has become a serious problem. As a result, there has been a great deal of attention given to new technologies for removal of heavy metal ions from contaminated waters. Biosorption is one such emerging technology which utilized naturally occurring waste materials to sequester heavy metals from industrial wastewater. The aim of the present study was to utilize the locally available agricultural waste materials for heavy metal removal from industrial wastewater. The wastewater containing lead and hexavalent chromium was treated with biomass prepared from ficus religiosa leaves. It was fund that a time of one hr was sufficient for sorption to attain equilibrium. The equilibrium sorption capacity after one hr was 16.95 ± 0.75 mg g-1 and 5.66 ± 0.43 mg g-1 for lead and chromium respectively. The optimum pH was 4 for lead and 1 for chromium. Temperature has strong influence on biosorption process. The removal of lead decreased with increase in temperature. On the other hand chromium removal increased with increase in temperature up to 40ºC and then started decreasing. Ion exchange was the major removal mechanism along with physical sorption and precipitation. The biosorption data was well fitted to Langmuir adsorption model. The kinetics of biosorption process was well described by the pseudo 2nd order kinetics model. It was concluded that adsorbent prepared from ficus religiosa leaves can be utilized for the treatment of heavy metals in wastewater.