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1.
Medical Journal of Cairo University [The]. 2003; 71 (2 Supp. 2): 167-172
in English | IMEMR | ID: emr-63632

ABSTRACT

The antiarrhythmic effects of magnesium sulfate were known long ago particularly in ventricular tachycardia and in torsade de points. This study reported the results of IV MgS04 in 30 patients with chronic AF. A prospective study conducted on 30 patients [12 males and 18 females with a mean age of 54 +/- 8.12] was carried out. Underlying heart disease comprised RHD in 9 patients, CAD in 5 patients and cardiomyopathy in 2 patients. The remaining patients had no structural heart disease. Following clinical evaluation, all patients had an infusion of MgS04 at a rate of 25mg/Kg following a bolus of 35-mg/Kg-body weight. The results revealed that of the 30 patients subjected to IV MgS04 infusion, 8 were successfully cardioverted to sinus rhythm over a mean period of 2 hours [ranging from 6-12 hours], while 10 patients had achieved rate control from a mean of 140/min to 100/min. over a period of 3 hours and twelve patients failed to respond. The study concluded that IV MgSO4 can be used successfully in the therapeutic cardioversion and/or rate control of AF particularly in patients with small left atrium


Subject(s)
Humans , Male , Female , Magnesium Sulfate , Infusions, Parenteral , Intensive Care Units , Treatment Outcome
2.
Medical Journal of Cairo University [The]. 2002; 70 (1): 191-203
in English | IMEMR | ID: emr-172564

ABSTRACT

In patients with acute exacerbation of chronic obstructive pulmonary disease, noninvasive ventilation may be used in an attempt to avoid endotracheal intubation and complications, associated with mechanical ventilation. We conducted a prospective, randomized study comparing noninvasive ventilation delivered through a face mask with standard treatment in patients admitted to ICU. A total of 23 patients were recruited from a large group of 63 patients with chronic obstructive pulmonary disease admitted to Critical Care Department. A total of 12 patients were randomly assigned to noninvasive ventilation [group I] and 11 to standard treatment [group 11]. The two groups had similar demographic characteristics with [mean age 51, 8 +/- 10 vs. 58.7 +/- 8.4, p=0.082 and weight 74.8 +/- 13.8 vs. 74.9 +/- 8.9, p 0.97] and clinical characteristics on admission to the hospital. The use of noninvasive ventilation significantly improved some of the final arterial blood gases and oxygenation parameters in successful cases. In selected cases with acute exacerbation of chronic obstructive pulmonary disease, noninvasive ventilation can reduce the need for endotracheal intubation and can improve the hypoventilation associated with the disease


Subject(s)
Humans , Male , Female , Pulmonary Ventilation , Length of Stay , Treatment Outcome
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