PUVA-induced skin cancer in dark-skin patient: a case report

Non-melanoma skin cancer is reported to be a cancer with highest prevalence in the world. Different risk factors have been identified, e.g., Genetic factors, skin-type, ethnicity, and iatrogenic. The main iatrogenic factors are radiation and drugs, mainly immunosuppressive medications, and oral psoralen and ultraviolet-A [PUVA]. It is known in the literature that exposure to more than 250 sessions of PUVA could be a risk for developing skin cancer. However, it was reported in fair skin patients. Herein, we report for the first time, a PUVA-induced basal cell cancer in a type-4 skin patient after receiving 400 sessions