Evaluation of piascledine 300 in the treatment of knee osteoarthritis clinical, biochemical and radiological study

In this work, the efficacy of piascledine 300 mg in the treatment of knee OA by clinical, biochemical and radiological study was evaluated. Forty patients with primary knee OA fulfill the ACR criteria for classification and reporting of knee OA were included and classified into two groups according to the presence or absence of effusion. The results have shown an improvement in the parameters measured, either clinically or biochemically, and a success rate of 65% of the drug as detected by clinical evaluation in this study after 6 months of drug intake, but the radiological study did not detect any signification changes