Non - histological assessment of liver fibrosis in HCV infection

In this study, a correlation between some serum markers [alanine aminotransferase/ aspartate aminotransferase [AST/ALT] ratio, level of matrix metalloproteinase 9 [MMP9], level of viremia and HCV serotype] and the severity of liver fibrosis in HCV-infected patients was detected. The study included 72 human cases referred to the Early Cancer Detection Unit for liver biopsy assessment. The severity of liver fibrosis was staged, using the METAVIR scoring system, into four stages. The level of viremia did not differ significantly in the different stages of liver fibrosis. Also, the type of HCV had no effect on the severity of liver fibrosis. However, transaminases ratio differed significantly in the different fibrosis stages. This serum test showed relative high sensitivity and specificity [92.6% and 94.38, respectively] in diagnosing severe fibrosis and cirrhosis. However, the level of MMB was inversely correlated with the fibrosis stages and was found to have 88.9% sensitivity and 88.6% specificity when diagnosing severe fibrosis and cirrhosis. Although, the sensitivity of these serum markers did not reach 100%, yet their use can reduce the number of liver biopsies when diagnosing and treating HCV-infected patients

Traumatic dental injuries of primary anterior teeth among preschool children in relation to social level

The work was conducted in an effort to study the relation between socioeconomic, level and prevalence of traumatic injuries to the primary teeth in preschool children in tanta. 1200 child were included in the study. They were randomly selected, their age ranged from 2-6 years. 600 child [300 boys, and 300 girls] enrolled from private kindergarden, and 600 [300 boys and 300 girls] from public once. Clinical and radiographic examination were done and adata collecting chart was designed for each child for recording the necessary information. The distribution of trauma was done according to [Ferguson and Ripa 1979]. The data was analysed statistically. The results showed that prevalence of traumatic injury was higher in boys than in girls and it was increased by age, due to increase activities in boys in both private and public schools. The private and public school education was used as a parometer to investigate the influence of social status. The results indicated that the prevalence of traumatic injuries to the primary anterior teeth in public schools increased than in private one, this was due to poor hausing facilities that lead to their playing out doors. On the other hand children from private schools had low% of prevalence to trauma this is due to dificient clubs, base ball equipment, roller skates and swimming pools either in homes or clubs as these population resides Tanta city which considered to some extent a rural community