ABSTRACT
Background: Blood cultures form a critical part of evaluation of patients with suspected sepsis. The present study was undertaken to study the risk factors, duration of incubation for obtaining positive cultures, and the clinical impact of the culture report. Methods: A total of 224 samples from 110 critically sick pediatric patients presenting with suspected bacteraemia were processed aerobically. Results: Cultures were positive in 25.45% of the Patients. Most of the positive cultures were obtained after 24 hours of incubation of the broth and no isolates were obtained beyond day 4 of incubation. Therapy was modified in 52.73% of the patients after receipt of culture report. Conclusions: Incubation beyond four days (unless with specific indication like enteric fever) may be unnecessary for issuing a negative culture report. Repeated isolation of doubtful pathogens confirms true bacteraemia. Early culture report increases therapeutic compliance.
ABSTRACT
We selected the pediatric urinary tract infection related research and review articles in English language using keywords or phrases such as Infant; children; culture; Escherichia coli; fever, UTI. Aims: The purpose of this review is to provide summary of the latest research in particular to the practical aspects of management of UTI in children. Background: Urinary tract infection (UTI) is an important medical entity commonly diagnosed during early childhood. Prevalence and incidence of UTI varies with age and gender. UTI can be missed just on history and clinical examination. Screening of UTI in high risk children is important and should be well balanced against cost and risk of missing UTI. Despite latest evidence from research there are still controversies in managing UTI in children. Conclusion: Despite major advances in management of UTI in neonates and children, uniform guidelines for the imaging and management of recurrent UTI are lacking, prompting a multinational large research project to fill in the knowledge gap.