comparative histological and ultrastructural study of the effect of hydrocortisone and prednisolone on the alveolar bone of rat offsprings

This work was carried out to investigate and compare between the defects of hydrocortisone and prednisolone on the developing alveolar bone of rat offspring, when therapeutic doses are administrated to the mothers during pregnancy. This was done to determine the safety profiles in using these glucocorticoides and this is by direct comparison with controls. From this study it was concluded that hydrocortisone is harmful if administered during pregnancy provided that it causes dangerous effects on the developing alveolar bone. So, it should be avoided completely during the pregnancy period. The alternate day prednisolone drug reduced the undesirable side effects on developing alveolar bone and should be replace the ordinary glucocorticoids if their use is a must

Abdominal aortic aneurysm: results of surgical treatment

Seventeen cases of abdominal aortic aneurysms were operated upon during a three years period [1985-1988]. Six patients were operated upon as emergency while eleven were managed electively. Mortality rate among the emergency group was 50% [three patients], only one of them died postoperatively Four of the emergency group presented with severe abdominal pain and shock, while two presented with a picture of internal hemorrhage. Mortality rate in the elective group was 9.1% [one patients], at the end of the operative procedure due to consumption coagulopathy. All AAA over 6 cm in diameter should be resected electively in spite of the absence of symptoms