Blood groups as risk factor of hypertension in Arar population, Northern Saudi Arabia

Background: Hypertension is a disease that has a huge impact on the health of communities. Familial patterns of hypertension suggests genetic factor as an another important non-modifiable predisposing factor, and ABO blood group is one of such factors which needs to be investigated in more details

Objective: to evaluate the prevalence of hypertension in various ABO and Rh blood group subjects, and to explore any association between ABO and Rh blood groups with hypertension. Methods: A cross-sectional study was conducted in Arar city, Northern Saudi Arabia. It included 312 participants from the general population of Northern Saudi Arabia. Data were collected by a pre-designed online questionnaire which was distributed among the population. It was self-administered, after a brief explanation of the idea of the research. The questionnaire included the clear questions to collect the relevant data

Results: the study included 312 participants 28.8% aged 30-39 years, 26.0% aged 40year or more, 85.3% were females and 79.2% were highly educated. In the studied sample, 38.1% had O blood group, 30.1% had B blood group, 26% had A blood group and 5.8% had AB blood group. About fifth [20.5%] of studied sample had hypertension; from them 20.3% group A, 7.8% AB, 25% B and 46.9% group O. The present study found that there was no significant association between hypertension and blood groups as risk factors [P = 0.274]. Among hypertensive cases 85.9% Rh +ve, 14.1% Rh -ve, there was no significant association between hypertension and Rh factor [P = 489]

Conclusion: The findings of the present study indicated that in Arar city population, we could not find any evidence that particular ABO blood group was more susceptible to develop hypertension

Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center / 대한배뇨장애요실금학회지

PURPOSE: Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC in children. METHODS: A retrospective analysis was conducted of 42 patients (31 males; mean age, 14.2±6.2 years) who underwent AC for neurogenic and nonneurogenic bladder dysfunction, with a median 12.0±1.5 years of follow-up. All patients underwent AC using the ileum with or without continent reconstruction. Pre-AC, concurrent, and post-AC procedures and complications were analyzed. Patients who underwent ureterocystoplasty, were lost to follow-up, or had less than 10 years of follow-up were excluded. The primary outcomes were the complication and continence rates, the post-AC linear rate of height and weight gain, and renal function. The Student t-test was used to evaluate between-group differences and the paired t-test was used to evaluate longitudinal changes in measured variables. RESULTS: Renal function was stable or improved in 32 of 42 patients (76.2%), with a post-AC continence rate of 88.1%. Thirty patients (71.4%) required 72 procedures post-AC. There was no statistically significant difference in the mean percentile of height (P=0. 212) or weight (P=0.142) of patients in the pre- and post-AC periods. No cases of bladder perforation or malignancy were detected. CONCLUSIONS: We consider AC to be a safe and effective procedure that does not negatively affect future physical growth, while achieving a good rate of stable renal function. Patients need long-term follow-up to address long-term complications.

Minimally invasive surgical approach to treat posterior urethral diverticulum

Urethral diverticulum is a localized saccular or fusiform out-pouching of the urethra. It may occur at any point along the urethra in both male and females. Male urethral diverticulum is rare, and could be either congenital or acquired, anterior or posterior. The mainstay treatment of posterior urethral diverticulum [PUD] is the open surgical approach. Here we discuss our minimally invasive surgical approach [MIS] in managing posterior urethral diverticulum