Functional status of the forearm and hand after radial artery procurement for coronary bypass operations

The Radial artery is being used frequently as a conduit of choice over the saphenous vein for coronary artery bypass. An important aspect in the use of the radial artery is the risk of ischemia, infection and neurologic dysfunction of the donor arm. This study included the follow up of the functional status of the forearm and hand in 112 patients who underwent coronary artery bypass using 112 radial arteries. The radial artery was harvested from the left forearm in 104 patients [92.9%] and from the right forearm in 8 patients [7.1%]. Forearm and hand complications occurred in 16 patients [14.3%]. No patients had acute ischemic injury of the hand. Ten patients [8.9%] complained of cutaneous paresthesia, at the time of discharge only 2 patients [1.8%] were complaining of paresthesia. Two patients [1.8%] had wound infection and were treated with antibiotics and wound infection healed in 7 and 9 days respectively. One patient [0.9%] had wound infection and dehiscence and required antibiotic treatment and seconday suture after 7 days. Seroma collection occurred in 2 patients [1.8%] that was treated by compression and was relieved by 9 days in both patients. Haematoma requiring surgical evacuation occurred in one patient [0.9%]. It also required lowering of the anticoagulation dose and operative drainage after 5 days of the operation. Follow-up was done from 4.5 months to 16 months [mean follow-up, 11 months]. Two [1.9%] of the ten patients [8.9%] complaining of paresthesia showed residual symptoms which improved in one patient after 3 months and in the other patient after 4.5 months. By paying attention to the harvesting technique of the radial artery, there would he an acceptably low risk of arm donor site complications in individuals undergoing coronary artery bypass grafting with the radial artery

Surgical versus chemical [Botulinum toxin] sphincterotomy for chronic anal fissure

This is a prospective randomized trial aiming to compare the effect of open lateral internal sphincterotomy versus Botulinum toxin injection in the treatment of chronic anal fissure. Thirty patients diagnosed as suffering from chronic anal fissure were randomly allocated into two groups. In the surgical sphincterotomy group [n =15] lateral internal sphincterotomy was done. In the Botulinum toxin group [n = 15] 20 U of type A botulinum toxin was injected into the internal anal sphincter. The injection was repeated two months later of complete healing was not accomplished. The patients were re-examined by inspection and re-evaluated for symptoms at 2, 6 and 12 months. Two months after treatment, the healing rate was 60% [9/15] in the BT group, and 93.5% [14/15] in the LIS group [p=0.031]. In the BT group 6 patients were offered a second injection at the second month. Six months after treatment one patient of the LIS group developed recurrences. Therefore, at six months the healing rate was 73.3% [11/15] in the BT group, compared to 86.7% [13/15] in the LIS group [p=0.36]. By 12 months post treatment, the healing rate remained stable in the LIS group 86.7% [13/15], while three patients in the BT group developed recurrence, resulting in an overall success rate of 53.3% [8/15] [P=0.046]. The return to daily activity was significantly longer in the LIS group [12.8 +/- 4.6 days] vs. [1 day] in the BT group [p<0.0001]. The incidence of complications in the sphincterotomy [4 cases of transient partial incontinence] group was significant as compared with none in the BT group [p=0.32]. In comparing the results of the two treatment modalities, BT injection was found to be inferior to LIS regarding the healing rates. On the other hand the BT therapy is easy to perform, can be done as an outpatient procedure, and associated with less complication. Considering these factors BT therapy might be valuable in selected patients with high surgical risks, or high incidence of future incontinence