ABSTRACT
【Objective】To observe the effect of Gastritis Prescription Ⅰ(GPⅠ) on the ultrastructure of gastric mucosa in spleen-deficiency atrophic gastritis(AG) patients.【Methods】Thirty chronic AG patients were treated with GPⅠ(mainly composed of Radix Codonopsis,Poria,Rhizoma Atractylodis Macrocephalae,Pericarpium Citri Reticulatae,Rhizoma Pinelliae,Fructus Amomi,Radix Angelicae Sinensis,Herba Taraxaci,Radix Paeoniae Alba,Radix Glycyrrhizae Preparata,etc.).The histological features of gastric mucosa sampled under gastroscope were observed before and after treatment under light microscope and electron microscope.【Results】After treatment,43.3% of moderate-degree and above atrophic area of gastric glands disappeared,and 16.7% became mild;36.7% of the disappeared gastric groove recurred and the thin gastric mucosa became normal.Microvilli of gastric gland became normal in 12 patients,accounting 54.5% in 22 patients with intestinal metaplasia.【Conclusion】GPⅠis effective in recovering the gastric mucosa of AG patients with deficiency of spleen and stomach Qi,and has an effect in counteracting intestinal metaplasia.
ABSTRACT
【Objective】To investigate the clinical characteristics of acute pancreatitis(AP) in Guangzhou area.【Methods】A retrospective analysis was carried out in 273 AP inpatients hospitalized in the First Affiliated Hospital of Guangzhou University of TCM from 1996 to 2004.The onset time,seasonal distribution,syndrome patterns and prognosis of PA,and sex,age and disease course of the patients in Guangzhou area were carefully analyzed.【Results】The incidence rate of AP in Guangzhou was increased in recent years,lower in summer while higher in winter.The male and the female had the same incidence(the ratio approaching to 1∶1).In terms of age,there was a lower incidence in teenagers and the highest in the group aged 20 to 39.The incidence reached a plateau in the group aged 40 to 79 and sharply decreased in the group aged 80 and over.In terms of disease course,the majority of the AP patients were much improved and left hospital within 1～2 week(s) and the frequency valve arrived at the peak about one week later.In terms of the prognosis,72.9% of the patients were cured after timely traditional Chinese and western medicine treatment,the fatality rate being 2.9%.In terms of syndrome patterns of AP,damp-heat in the liver-gallbladder accounted for 69.9%,liver and Qi stagnation 11.7%,phlegm-stasis blocking collaterals 7.8%,deficiencycold in fu-organs 7.3% and excess in Yangming fu-organ 3.4%.【Conclusion】The incidence rate of AP in Guangzhou area tends to increase in recent years,the young and the middle aged have the highest incidences,most cases are manifested as damp-heat in the liver-gallbladder pattern,and AP attack usually occurs in winter and spring,and holidays,indicating that AP attack has a relation with unhealthy lifestyle,especially improper diet,in developed areas.This should be taken into consideration by the department concerned.