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Chinese Journal of Primary Medicine and Pharmacy ; (12): 1767-1768, 2012.
Article in Chinese | WPRIM | ID: wpr-427794

ABSTRACT

Objective To explore the clinical effect of small cell lung cancer(SCLC) treatment with recombinant human endostatin injection and cis-platinum complexes.Methods 100 patients with SCLC were divided into 2groups.The experiment group used cis-platinum complexes while the control group used recombinant human endostatin injection.Results The effective rate of experiment group was obviously higher than the control group ( 74.0% vs60.0%,x2=2.16,P < 0.05 ).The median survival time of experiment group was better than control group( t=2.02,P < 0.05 ).The diverse of untoward effect of two groups had no difference ( P > 0.05).Conclusion Recombinant human endostatin injection and cis-platinum complexes were better therapy for SCLC,which had stable effect,no severe untoward effect and overcome the drug-fast of cis-platinum complexes.

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