ABSTRACT
Purpose: Despite the availability of a large number of commercial denture cleansing products, only a few are used by wearers of dentures. This may be due to negligence on the part of the wearers of dentures and or the high cost of the products. We, therefore, felt inspired to study the antifungal effect of different materials usually available in the kitchen
Materials and Methods: One hundred and sixty resin acrylic samples were prepared and divided into three groups of 50 samples each and immersed into variable concentrations of: Sodium chloride [Group I], Sodium bicarbonate [Group II], and vinegar [Group III]. In addition, 10 samples were immersed into water as a control group [Group IV]. Minimum inhibitory concentration and the minimum immersion time needed were studied for each group
Results: The solutions were only found to be effective against Candida albicans in concentrations higher than 50 ml/200 ml, 10 g/200 ml and 5 g/200 ml of vinegar, sodium bicarbonate and sodium chloride respectively. The same concentrations were more effective when acrylic resin plates were immersed for 8 hours rather than 1 hour [P < 0.05]
Conclusions: Sodium chloride, sodium bicarbonate and vinegar are not strong enough as denture cleansing agents in low concentrations. However, high concentrations used for 8 hours might be helpful for the user of dentures
ABSTRACT
The role of qat chewing habit in developing oral and GIT cancer still questionable. This stimulated us to conduct this immunohistochemical study, which aims to evaluate the proliferating activity of the epithelial cells in the oral mucosa of qat chewers. This study was done on 40 biopsies taken from the buccal mucosa of qat chewers who chew on one side only. Of them 20 biopsies were taken from the chewing side and the other 20 biopsies were taken from the opposite side. With all cases, ki67 marker was used to evaluate the proliferating activity of cells. Results of this study showed positive staining in the basal cells of the epithelium in all cases 100% [n=40], and positive staining in the supra-basal cells of 45% of study group cases [n=20], while it was negative in the supra-basal cells in all cases of control group [p=000.6]. However, all cases with positive staining of supra-basal cells in study group affected the layers directly subjacent the basal layer. In conclusion qat chewing may play a positive role in the proliferating activity of epithelial cells, but these pathological changes are not considered as atypia because they did not affect the squamous cells. These changes can be diagnose as crowding of epithelial cells, which classified as mild epithelial dysplasia