ABSTRACT
Objective To evaluate the diagnostic value of quantitative tissue velocity imaging ( QTVI ) in the detection of right ventricle function in a rabbit model of pulmonary artery embolism .Methods Twenty-two healthy adult rabbits were used in this study .The animal models of acute pulmonary embolism were created by injecting gelatin sponge into the ear vein of rabbits .The changes of right ventricle function were dynamically observed at immediately , 1 week, and 3 weeks after the establishment of acute pulmonary embolims models .QTVI images of the 4-chamber view at cardiac apex were recorded and analyzed by off-line analysis.Results The VP was significantly reduced immediately after the models were built compared with the data before modeling in both the basal and middle segments , the TQ-S was prolonged , and Ve/Va>1 (P<0.05).The VP at1 week after modeling was not significantly decreased than the data before modeling in both the basal and middle segments , and the TQ-S was prolonged, but the Ve/Va ratio was <1 (P<0.05).At 3 weeks after modeling, the VPwas decreased compared with the data before modeling , and the Ve/Va ratio was <1 (P<0.05). The intra-group comparison showed that the V P of the basal segment of right ventricle free wall was enhanced than that of the middle segment (P<0.05), butTQ-S was not obviously prolonged in both the two segments .Conclusions Quantitative tissue velocity imaging can reflect the contraction and relaxation of right ventricle in rabbits precisely .It is a good method to evaluate the function of right ventricle in animal models of pulmonary artery embolism.
ABSTRACT
Objective To investigate the role of modified Seldinger technique combined with vascular ultrasonography in the placement of peripherally inserted central catheters (PICC) in patients with breast cancer undergoing postoperative chemotherapy.Methods Totally 120 patients with breast cancer undergoing postoperative chemotherapy were equally divided into the observation group and the control group using the table of random number.In the observation group,PICC were placed using the modified Seldinger technique combined with vascular ultrasonography; in the control group,the PICC were placed using the traditional blind puncture technique.The success rate of first puncture,success rate of first placement,and the incidences of mechanical phlebitis and thrombosis were compared between two groups.Results The success rate of first puncture,success rate of first placement,and the incidences of mechanical phlebitis were 91.67％,100％,and 3.33％,respectively,in the observation group and 76.67％,86.67％,and 45％,respectively,in the control group (P =0.0061,P =0.0434,and P ＜ 0.0001).However,no significant difference was found on the incidence of thrombosis between the two groups (P =0.1187).Conclusion Modified Seldinger technique combined with vascular ultrasonography is efficient and safe for PICC placement for patients with breast cancer undergoing postoperative chemotherapy.