ABSTRACT
Objective: To evaluate changes in serum lipoproteins in primiparous women with eclampsia and compare it with pregnant women having normal blood pressure
Methods: This cross sectional study was conducted on 65 primiparous eclamptic patients and 21 normotensive pregnant women in the tertiary care hospitals of Peshawar. History of each woman was recorded on a questionnaire. Blood pressure was measured using standard methods. About 5 ml of venous blood was drawn for the analysis of lipoproteins
The data was analyzed using computer software package SPSS version 10. The P value <0.05 was considered statistically significant
Results: Mean age of hypertensive cases was 23.2 +/- 0.52 years while that for controls was 23.9 +/- 1.16 years. Significant differences were found in serum lipoproteins. Women having eclampsia had 28.8%, 29.5%, 31.1%, 32.9% and 65.3% higher, low density lipoprotein-cholesterol [LDLC], triglycerides [TG], total cholesterol [TC]:high density lipoprotein-cholesterol [HDLC] ratio, LDLCiHDLC ratio and TG:HDLC ratio respectively as compared to the control group. The HDLC concentrations, HDLC:VLDLC ratio and apolipoprotein-A1 level were 26.9%, 56.6% and 27.9% respectively, lower in the patient group as compared to the controls
Conclusion: This study suggests that evaluation of lipoprotein concentrations during antenatal period can be helpful in the early detection and prevention of developing eclampsia
ABSTRACT
To determine the frequency of ABO blood group and Rhesus [Rh] D antigen in the females of "District" Peshawar, Khyber Pakhtunkhwa Province, Pakistan. This cross-sectional study was conducted on 429 women having pregnancy induced hypertension, admitted in the three teaching hospitals of Peshawar, over a period of one year. Blood sample was collected from each subject after taking informed consent. The antigen antibody agglutination slide test for "blood grouping [ABO]" and RhD factors was done by using IgM and IgG monoclonal reagents. The antisera used were from Biolaboratory, USA. Data was analyzed for percentage calculation. The blood group distribution was 134 [31.2%], 43 [10.1%], 116 [27%], 136 [31.7%] for blood groups A, AB, O and B, respectively. Subjects having blood group B was slightly more dominant, followed by A and O, while blood group AB was rare in these females. Blood group A Rh negative is more in female 12 [37.5%] followed by group O 10 [31.3%], group B 09 [28.1%] and group AB 01 [3.1%].Frequency of "Rh-positive blood group" is B, A, O and AB, whereas the frequency of the most common Rh-negative blood group are A, O, B and AB respectively. The determination of the frequency of blood groups in the region would not only help in blood transfusion services, but also reduce the risk of erythroblastosis foetalis in the neonates
ABSTRACT
This study aimed to determine the frequency of depression among patients with type-II diabetes mellitus in Peshawar at Khyber Teaching Hospital, Peshawar, from March to September 2010. Depression was assessed by using Beck Depressive Inventory-II [BDI-II]. Out of 140 patients with type-II diabetes, 85 [61%] were women and 55 [39%] were men. Mean age was 45 +/- 7.45 years. Eighty four [60%] patients presented with severe depression. Depression was higher in females than males and widows. Depression was high in diabetic patients, especially in females and widows. It is of essence that psychiatric attention may be necessary to be incorporated in diabetes care both for prevention and treatment
Subject(s)
Humans , Male , Female , Diabetes Mellitus, Type 2ABSTRACT
Fifty patients who underwent surgery for perforation of appendix were studied. Age of the patients ranged from 15 to 45 years. The disease manifested as localized peritonitis in 18 cases [36%] and as diffuse peritonitis in 32 cases [64%]. In all the patients, combination antibiotic therapy was used to combat aerobic and anaerobic organisms. There was no mortality in the localized peritonitis group while 3 patients with diffuse peritonitis died [6%]. Early I surgery is advisable in the cases of perforated appendices to reduce morbidity and mortality