ABSTRACT
Community-acquired pneumonia is a common disease and a frequent cause of morbidity and mortality worldwide. Streptococcus pneumoniae is the most common cause of community-acquired pneumonia. The current study was conducted to determine the serotype distribution and antimicrobial susceptibility patterns of Streptococcus pneumoniae isolated from patients with community-acquired pneumonia at Assiut University Hospitals. From February 2013 to May 2013, sputum samples from 60 adult patients with community-acquired pneumonia were analyzed for bacterial etiology using conventional methods. Antimicrobial susceptibility and serotyping of Streptococcus pneumoniae was performed, bacterial agents were detected in 53 patients [88%]. Streptococcus pneumoniae was the most common [30%] isolated bacteria. Eight co-infections were identified. The detected pneumococcal-serotypes were in decreasing order; 1, 9V, 6B, 19F, 23F, 14, and 19A. Pneumococcal-antibiotic resistance was highest for penicillin and ampicillin antibiotics. Streptococcus pneumoniae is the most common isolated bacteria in cases of community-acquired pneumonia which is associated with certain serotypes. Resistance to penicillin and other antimicrobial agents increased rapidly during the last years among pneumococcal strains worldwide