ABSTRACT
Background: Children’s participation is crucial in research on childhood diseases and cases associated with childhood health. Despite the existence of many publications that address ethical issues related to the participation of children in clinical research around the world, very little has been written about these ethical issues from an Islamic perspective. Methods: In this study, we analyzed medical research on children from three Islamic resources: plural fatwas by juristic institutions, the opinions of Islamic medical organizations and individual writings. Results: Seven plural fatwas from three juristic councils could be found. Only four of them raise ethical concerns about research on children. Two documents from medical organizations were identified. Conclusion: Three different positions could be concluded from these fatwas: a total prohibition, prohibition unless and permission. Prevention any harm is a major concern in all fatwas. Guardian's consent is necessary, but more details are needed. The guidelines of Islamic Organization of Medical Sciences IOMS reflect the best available Islamic perspective about research on children.