ABSTRACT
The antisickling properties of fermented mixture of dried unripe fruit pulp of Carica papaya and dried Sorghum bicolor leaves; mixed in equal proportions in distilled water; was carried out using sodium metabisulphite sickled red blood cells and the result presented. Equal weight of dried C. papaya fruit pulp and S. bicolor leaves were fermented together in distilled water at room temperature and the aqueous extract obtained and used for antisickling assays. The extract gotten from the materials incubated for 5 days indicated as SP5; was found to have the highest antisickling properties with 93inhibitory and 84reversal activities. The concentration of the day 5 extract was further varied. 0.2 ml was found to be the optimum volume of the test extracts