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Arq. bras. cardiol ; 89(1): 60-63, jul. 2007. tab
Article in Portuguese | LILACS | ID: lil-459817

ABSTRACT

O ecocardiograma sob estresse com dobutamina é um método bem estabelecido para avaliar doença arterial coronária, cuja sensibilidade tem sido potencializada pela adição de atropina no final do protocolo. Indivíduos com glaucoma, doença com alta prevalência em pacientes cardiopatas com mais de 40 anos, não podem se beneficiar do uso de atropina por ser contra-indicada neste grupo. Além disso, estes indivíduos são tratados freqüentemente com betabloqueadores tópicos (colírios), que podem exercer efeitos sistêmicos diminuindo a freqüência cardíaca, pressão arterial e capacidade pulmonar. O objetivo do nosso trabalho foi verificar se a ocorrência de um possível efeito sistêmico causado por estes colírios, causando baixa resposta cronotrópica, poderia determinar resultados inconclusivos no ecocardiograma sob estresse pela dobutamina nestes pacientes com glaucoma.


Dobutamine stress echocardiography is a well-established method to assess coronary artery disease, of which sensitivity has been enhanced by adding atropine at the end of the protocol. Individuals with glaucoma, a disease with a high prevalence in patients with cardiac diseases older than 40 years, cannot benefit from the use of atropine as it is contraindicated for this group of patients. Additionally, these individuals are often treated with topical betablockers (eye drops), which can have systemic effects by decreasing cardiac frequency, blood pressure and pulmonary capacity. The aim of our study was to verify whether a possible systemic effect caused by the use of these eye drops, yielding a low chronotropic response, could result in inconclusive dobutamine stress echocardiography in patients with glaucoma.


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Cardiotonic Agents , Dobutamine , Echocardiography, Stress , Glaucoma/drug therapy , Ophthalmic Solutions/therapeutic use , Analysis of Variance , Blood Pressure/drug effects , Case-Control Studies , Chi-Square Distribution , Cardiotonic Agents/administration & dosage , Cardiotonic Agents/adverse effects , Coronary Disease , Dose-Response Relationship, Drug , Dobutamine/administration & dosage , Dobutamine/adverse effects , Heart Rate/drug effects , Rest
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