ABSTRACT
This short study aims to determine the prevalence of various bacterial pathogens causing infections in the Aseer regions, and to also assess the distribution of Staphylococcus aureus in relation to different body sites as well as their in vitro antimicrobial susceptibility profile. Clinical specimens [n=9831] from various infections diagnosed at Aseer Central Hospital [ACH] and Abha General Hospital [AGH], were analyzed bacteriologically. Confirmed S. aureus isolates [n=210] were tested against 44 antibacterial agents as per standard methods. Bacterial pathogens were recovered from 24.9% of the samples. The results revealed that Escherichia coli, Klebsiella pneumoniae, Enterococcus spp. and S. aureus to be the main etiological agents, while purulent exudates of wounds and abscesses were the main source ofS. aureus. Out of the 210 S. aureus isolates; 77 [38.5%] were recovered from purulent exudates of wounds and abscesses of the examined patients and 53 [26.5%] were from high vaginal discharges, while other body sites exhibited different rates of S. aureus. On the other hand, 45% of the 210 S. aureus isolates were found to be multidrug resistant S. aureus [MRSA]. The results from this study revealed that Escherichia coli and staphylococci were the main etiological agents, while purulent exudates of wounds and abscesses were the main source of S. aureus. Also, a higher rate of MRSA was detected