ABSTRACT
Diabetes mellitus is a metabolic disorder, that affects almost all the cells of the body. Well documented complications of DMinclude, neuropathy, nephropathy, microangiopathy, and retinopathy. The negative impact of the disorder is also found inother cells, including male reproductive system. In this study, fifty adult Wistar albino male rats were used. The rats weredivided into 10 groups, each group comprised of 5 rats. Diabetes was induced by intraperitoneal injection of STZ, effects ofDM were observed on the sperm producing cells then preventive as well as curative effects of Metformin, Punica granatum,Nigella sativa and Zingiber officinale were observed. It was found that all the substances prevent as well as repair/cure thedamage caused by DM to the seminiferous tubules and other structures. The results of this study show that Metforminthough prevented and caused repair to the damaged cells as well, but was not as effective as Punica granatum, Nigellasativa and Zingiber officinale.
ABSTRACT
A five-year-old male Doberman pinscher with an oval-shaped mass in the left side of thorax, respiratory distress, and an impairment of the use of the left forelimb was referred to the Faculty of Veterinary Medicine of ShahidChamran University in Ahvaz. Radiographs were taken. The abnormal mass was removed by radical surgery. Histopathological examination confirmed the occurrence of a well-differentiated canine osteosarcoma. The case was re-examined after approximately 15 months, which revealed a large mass in the left side and metastases in the right thoracic wall and lung. The decision was taken to euthanize the patient and a necropsy was performed. The recommended treatment for canine osteosarcoma is the removal of the primary tumor followed by adjuvant chemotherapy, but recurrence is common