ABSTRACT
Background: Varicocele is a collection of dilated veins in the pampiniform plexus that drain the testicle and may contribute to male infertility. A variety of surgical and non-surgical approaches have been advocated for varicocele treatment
Objective: Evaluate laparoscopic varicocelectomy with regard to intra and post-operative parameters
Patients and Methods: At Departments of urology of Al_azhar University Hospitals [Damietta]. Prospective randomized study was performed about laparoscopic varicocelectomy during the period from June 2016 to December 2017 after obtaining informed consent. The group included patients with clinically palpable varicocele confirmed by U/S complaining of infertility [primary, secondary] or chronic testicular pain
Results: The range operative bilateral Laparoscopic Varicocelectomy time was 60-90 minutes. There were no intra operative complications in the study group. The average hospital stay was 24-36 hours. Post-operative analgesics [2-3] doses, daily activities initiation usually started after 4-5days. Hydrocele formation was seen in [11.1%] patients recurrence was seen in [5.6%] patient. None of the patient has developed an atrophic testis as a result of the laparoscopic procedure. Patients had improvement of the seminal fluid parameters during follow up period and pregnancy rate was [25%]
Conclusion: Laparoscopic varicocele ligation is a simple and safe technique causing minimal morbidity and enabling rapid return to normal activity
ABSTRACT
Background and study aims: obscure gastrointestinal bleeding [OGIB] is defined as bleeding of unknown origin that persists or recurs after an initial negative investigation. Identifying the source of OGIB represents a diagnostic challenge that is frequently focused on visualizing the small intestine. Conventional diagnostic methods, such as push enteroscopy, small-bowel follow-through, radionuclide scanning, and angiography, each exhibit inherent limitations. Double balloon enteroscopy [DBE] was designed specifically to evaluate the entire small bowel. DBE allows for better visualization, biopsy of the identified lesions and application of therapeutic techniques. This study sought to assess the role of DBE in the diagnosis and management of patients with OGIB
Patients and methods: this prospective study was conducted to analyse data from 31 patients presenting with OGIB referred for DBE in the Endoscopy Unit at the Internal Medicine Department of the Faculty of Medicine, Cairo University
Results: five patients had lesions in locations other than the small intestine that accounted for GI bleeding. Thus, the potential source of OGIB was defined as the small intestine in 18 of 26 patients [69.2%], and negative DBE findings were noted in eight patients [30.8%]. Major findings included small intestinal tumours in eight patients, vascular bleeding lesions in 8 patients and ulcerations in 2 patients. Endoscopic haemostasis was performed in eight patients with vascular lesions. The three patients with Petuz-Jegher syndrome underwent polypectomy of their major polyps. Patients with gastrointestinal tumours were referred for surgery
Conclusion: DBE is an excellent endoscopic procedure that has a relatively high diagnostic and therapeutic yield. The procedure is feasible and exhibits a high safety profile with a low complication rate when performed by an experienced endoscopist
ABSTRACT
Objective To evaluate Brachychiton acerifolius leaf extracts as antidiabetic potential agent and to identify the main active constituents using bioactivity guided fractionation. Methods In vitro antioxidant activity was evaluated for B. acerifolius different extracts using DPPH assay and vitamin C as control. Antidiabetic activity was then determined using STZ-induced rats treated daily with ethyl acetate and 70% ethanol leaf extracts for 4 weeks at a dose of 200 g/kg body weight against gliclazide reference drug. Blood glucose, α-amylase, lipid profile, liver function enzymes and oxidative stress markers were assessed along with histopathological study for liver and pancreatic tissues. Isolation and structural elucidation of active compounds were made using Diaion and Sephadex followed by spectral analyses. Results The results indicated that ethyl acetate and ethanol leaf extracts exhibited the strongest antioxidant activity compared to that of vitamin C (IC
ABSTRACT
Only 20% of patients with pancreatic cancer undergo curative resection. Therefore palliative treatment of pancreatic cancer assumes the utmost clinical importance. The aim of palliative treatment of pancreatic head carcinoma is to relieve the jaundice and/or duodenal obstruction. Endoscopic decompression of the obstructed biliary system can be accomplished in most cases, but the durability of that technique is not as great as that of a surgically created bypass. Many authors reported with open, hepaticojejunostomy higher morbidity and mortality rate than the former nonsurigcal methods. In order to promote long lasting palliation with low morbidity and mortality rates, minimally invasive palliative treatment using laparoscopy can be used. This study was done on 10 patients with advanced pancreatic head cancer. Cholecystojejunstomy, and jejunojenostomy were done in all patients as a palliative bypass for obstructive jundice while gastrojejunostomy was done only in 3 cases for impending duodenal obstruction. The results were encouraging as regard shorter hospital stay, no perioperative mortality and less post operative complications