ABSTRACT
Background: To report a case of orbital dirofilariasis from a patient in Abadan city Southwest Iran
Case report: A 54- year- old woman referred to Abadan oil company hospital, Southwest Iran with the symptoms of tearing, irritation, swelling, and itching of the right eye. In ophthalmoscopy, a live worm was observed in sub- conjunctival space. The worm was removed and sent to the laboratory. The worm was white in color with a length of 105 mm. Based on morphological characterization identified as Dirofilaria repns
Results: We found that vitamin D3 suppresses the mRNA expression of TLR2 and TLR4 in patients with type II diabetes. TLR2 and TLR4 expression in the patients exposed to vitamin D3 were significantly decreased in comparison with patients who were not treated with vitamin D3
Conclusion: This is the second report of ocular dirofilarisis from Southwestern tropical region of Iran. Increasing of human dirofilariasis may be attributed to environmental changes with global warming, humidity and increase of mosquito vectors and breeding, agricultural development and change in social conditions, traveling and outdoor living
ABSTRACT
Background: dirofilariasis is a common helminthic parasitic disease in both domestic and wild animals around the world, with canines as the principal reservoir host and mosquitoes as the vector. Human dirofilariasis has been reported from many parts of the world, including Africa, Australia, the Americas, Europe, and Asia
Case Report: a 40 year old woman from Abadan city Southwest of Iran referred to surgeon with a nodule on her right breast. Ultrasound and mammography revealed a nodule diagnosed as parasitic lesion. After resection of the nodule, tissue was placed in 10% formaldehyde and sent to pathology laboratory. In histopathological examination, cross section of a worm surrounded with necrotic tissue, associated with infiltration of Neutrophils, Eosinophils, and foreign body giant cells observed which was morphologically compatible with Dirofilaria repens
Conclusion: human dirofilariasis should be considered in endemic regions