ABSTRACT
Objective: To determine the effect of Bifidobacterium BB12 on mean change in stool frequency and hospital stay in the management of acute diarrhea. Study Design: Randomized controlled trial. Place and duration of study: Study was conducted at department of pediatrics. DHQ hospital, Faisalabad from 1[st] July 2013 to 31[st] December 2013
Patients and methods: Ninety eight patients after fulfilling inclusion criteria were registered and sorted out into group A [study] and Group B [Control] randomly [By lottery method]. Group A patients were given Bifidobacterium BB12 [6 Billion units BD for five days] diluted in ORS while group B patients were given ORS only. The cases were assessed daily for decrease in frequency of stool and total duration of illness at discharge
Results: Mean age at the time of admission was 17.6 +/- 7 months for study group and 14.6 +/- 7.4 months for controls. Duration of hospital admission was 1.88 +/- 0.21 days in the probiotic group compared with 3.38 +/- 0.13 days in the control group [P = 0.02]. Mean reduction in the frequency of stool per day was 5.08 +/- 0.34 times for study group and 2.3 +/- 0.35 times for the control group [P = 0.05]
Conclusion: We conclude that effect of Bifidobacterium bifidum is statistically significant in reducing the mean change in stool frequency and hospital stay in management of acute diarrhea in children
ABSTRACT
To compare the efficacy of intravenous magnesium sulfate and conventional treatment with conventional treatment alone in acute severe asthma in children of age group 5 to 15 years known cases of bronchial asthma. Randomized control trial. Indoor and outdoor patients of pediatrics department of DHQ hospital, Faisalabad. Six months. In this study, 43.58%[n=17] in Exposed and 53.85% [n=21] in Un-exposed group were male and remaining 56.42%[n=22] and 46.15%[n=18] were females, mean pulse rate in both groups was recorded which shows 97.32 +/- 6.58 in Exposed Group and 103.67 +/- 8.32 in Un-exposed Group, p value was calculated as 0.02, mean FEV1 rate in both groups was recorded which shows 60.32 +/- 7.56 in Exposed Group and 54.07 +/- 6.43 in Un-exposed Group, p value was calculated as 0.03. We concluded that intravenous magnesium sulfate along with conventional treatment is significantly better than conventional treatment alone for the management of acute severe asthma attack
ABSTRACT
Objective: To compare the efficacy of normal saline and inhaled beta-agonist in the treatment of bronchiolitis
Study design: Randomized clinical trial
Settings: The study was conducted in Paediatric Medicine Department, DHQ hospital/Punjab Medical College Faisalabad. Period: 06 months from 1[st] October 2013 to 31[st] march 2014
Results: In this study, 58.33%[n=21] in Group-A and 66.67%[n=24] in Group-B were between 0-9 months of age, mean and sd was calculated as 11.43 + 3.87 months in Group-A and 10.52 +/- 3.32 months in Group-B, 52.78%[n=19] in Group-A and 61.11%[n=22] in Group-B were male while 47.22%[n=17] in Group-A and 38.89%[n=14] were females, mean clinical score in both groups was recorded as 4.11+1.32 in Group-A and 5.65 + 1.89 in Group-B, comparison of efficacy in both groups was recorded which shows 58.33%[n=21] in Group-A and 25%[n=9] in Group-B were treated effectively while rest of 41.67%[n=15] in Group-A and 75%[n=27] in Group-B were not treated effectively, p value was calculated as 0.008, which is statistically significant
Conclusions: The results of this study reveal that inhaled beta-agonists are more effective than normal saline