Erratum: Associations between Dietary Allium Vegetables and Risk of Breast Cancer: A Hospital-Based Matched Case-Control Study / 한국유방암학회지

This article was initially published on the Journal of Breast Cancer with a misspelled author name and affiliation of the seventh author.

Associations between Dietary Allium Vegetables and Risk of Breast Cancer: A Hospital-Based Matched Case-Control Study / 한국유방암학회지

PURPOSE: The protective effect of Allium vegetables against carcinogenesis has been reported in experimental studies particularly focusing on the gut. Therefore, we conducted a hospital-based matched case-control study to explore the association between dietary Allium consumption and risk of breast cancer among Iranian women in northwest Iran. METHODS: A validated, quantitative, food frequency questionnaire was completed in 285 women (aged 25–65 years old) newly diagnosed with histopathologically confirmed breast cancer (grade II, III or clinical stage II, III) in Tabriz, northwest Iran, and the completed questionnaires were included in an age- and regional-matched hospital based-control study. The odds ratios (ORs) and 95% confidence intervals (95% CI) were estimated using conditional logistic regression models. RESULTS: Multivariate analysis showed that there was a negative association between the consumption of raw onion and risk of breast cancer after adjustment for covariates (OR, 0.63; 95% CI, 0.40–1.00); however, this association was insignificant. On the other hand, there was a positive association between consumption of cooked onion and risk of breast cancer, after adjustment for covariates (OR, 1.54; 95% CI, 1.02–2.32). However, reduced risk of breast cancer was associated with higher consumption of garlic and leek with adjusted ORs of 0.41 (95% CI, 0.20–0.83) and 0.28 (95% CI, 0.15–0.51), respectively. CONCLUSION: Our findings suggest that high consumption of certain Allium vegetables, in particular garlic and leek, may reduce the risk of breast cancer, while high consumption of cooked onion may be associated with an increased risk of breast cancer.

Red cell distribution width levels and disease activity in ulcerative colitis

The amount of literature concerning the implication of the red cell distribution width [RDW] in the assessment of ulcerative colitis [UC] activity is rather limited. The aim of this study is to investigate the potential role of RDW in the evaluation of UC disease activity. A total of 96 patients with UC and 51 age and sex-matched healthy volunteers were included in a cross-sectional study. Clinical disease activity was defined using the numerical Disease Activity Index [DAI]. In addition to RDW, serum C-reactive protein [CRP] levels, erythrocyte sedimentation rates [ESR], and platelet counts [PLT] were measured. AThere were 47 [about 49%] patients with that had active UC. The RDW was significantly higher in patients with UC than in controls [p=0.001] and active versus patients in remission [p<0.001]. RDW was significantly correlated with DAI scores, ESR, CRP and PLT in active patients. There was a significant correlation between RDW with DAI scores and CRP levels in patients who were in remission. RDW was elevated in UC patients in comparison with healthy controls and increased markedly in active disease. It was also strongly correlated with clinical disease activity scores and inflammatory parameters such as ESR and CRP. RDW, as a cost-effective tool, may be an additional parameter to assess disease activity in UC.