ABSTRACT
Background and Aim: we described the presentation, management and subsequent treatment outcomes of children and adolescents diagnosed with a pituitary adenoma in a joint neuroendocrine setting followed up by a single service as well as assessing long-term outcomes in terms of endocrine status and neurology symptoms
Methods and Materials/Patients: a total of 21 participants with histologically verified pituitary adenoma between January 2011 and June 2014 were studied. Patients' data from clinical, radiological and pathological records were analyzed using SPSS [Version 16]
Results: all these children and adolescents with pituitary adenomas were managed with microscopic transsphenoidal surgery. The most common symptom was Cushing [47.6%, n=10]. The functional type [76.2%, n=16] was more than the non-functional. The post-operative control MRI of most of them was clear [90.5%, n=19]. The lab control of most of them was normal [76.2%, n=16]. Apoplexy was seen in 5 patients [33.8%]. Gross-total resection [GTR; 100% tumor removal as judged by early post-operative imaging] was achieved in 19 cases. Only one of these patients showed evidence of radiologic recurrence
Conclusion: in our study, all patients underwent microscopic transsphenoidal surgery due to limitation of endoscopic approach in pediatric and avoided wide anatomical deficit. Doing a comparative study between these two approaches will bring about promising results