Two dose prophylactic antibiotic-role in prevention of wound infection in clean and clean contaminated surgical wound

This prospective study was carried out in surgical unit 7 Dow Medical College and Sindh Government Lyari General Hospital Karachi from September 1997 to July 1998. Thirty patients belonging to different surgical problem were included. Diabetic and immunodeficientpatients were excluded from study. Patient age ranged between 2-70 years. Mean duration of operation was 40 minutes. One patient [3.3%] developed deep wound infection in clean surgical would and needed restarting of antibiotics. However, results of two dose first generation cephalosporins as prophylactic antibiotics are encouraging even in hospitals situated in neglected areas of metropolitan city like Sindh Government Lyari General Hospital Karachi