Frequency of HBs Ag and anti-HCV in trauma patients

This study was carried out to determine the frequency of Hepatitis B and C Viral infection in patients undergoing emergency surgical operations after trauma, and to evaluate the associated risk factors. Descriptive Study. This study was conducted at General Surgical, Orthopaedic and Paediatric Surgery Department of Ghulam Muhammad Mahar Medical College Hospital Sukkur from May-2011 to April-2012. All the patients who were admitted in the Surgical and orthopaedic department for emergency surgical operations followed by trauma were included in the study. The patients were screened for HBsAg and Anti-HCV using immunochromatography [ICT] method. Those who were weak positive by ICT were further confirmed by Enzyme Linked Immunosorbent Assay [ELISA]. 592 patients were admitted in Surgical and orthopaedic department during a period of last one year for emergency operations after trauma and were screened for HBsAg and Anti-HCV. Out of these 592 patients 472 [79.7%] were males and 120 [20.27%] were females. Mean age of these patients was 40 years. After screening, 33 [5.57%] patients were found HBsAg positive and 117 [19.76%] were Anti-HCV positive, while 09 [1.5%] were positive for both. Hepatitis-B was found in 21 [2.3%] males and 12 [1.3%] females, while Hepatitis-C was predominantly found in 68 [7.44%] males and 49 [5.36%] female patients. Parenteral injections by Quacks, previous surgery, blood transfusion and shaving by barbers were found to be the risk factors. High frequency of HBs Ag and Anti-HCV was found in trauma patients undergoing emergency surgery. Our message is that "Prevention is better than cure". So it is essential to prevent the spread of Hepatitis B and C by screening every patient before surgery and counseling of patients

Frequency of hepatitis D CO and super infection in hepatitis B patients

To determine the frequency of co/super infection of hepatitis D in patients with hepatitis B related liver disorders. Descriptive study. The hepatitis Centre Ghulam Mohammad Mahar Medical College Hospitals Sukkur and Khairpur, from January 2009 to December 2009. All patient registered for HBV associated infections were selected. Blood was drawn from 200 patients who fulfilled the inclusion criteria. Those with an incomplete test profile were excluded. All clinical conditions were investigated through liver function tests, coagulation profile, abdominal ultrasonography, upper gastrointestinal endoscopy and liver biopsy. Liver cirrhosis and hepatocellular carcinoma [HCC] were diagnosed either on the basis of histology, or on a combination of radiological, endoscopic and laboratory data. Hepatitis B virus DNA was extracted from serum by real time PCR. Descriptive statistics were used for frequency and mean determination. The 129 patients finally selected for statistical analysis included 108 [84%] males and 21 [16%] females. The ages ranged from 6-68 years [mean=31.5 +/- 12.39 years]. There were 70 [54.2%] patients of non-cirrhotic, chronic hepatitis [CLD], 38 [29.4%] carriers, 12 [9.3%] cirrhotic and 9 [6.9%] hepatocellular carcinoma [HCC] patients. Among the 129 patients, 45 [34.9%] were positive for double infection with HDV. These included 35 CLD cases, 7 cirrhotic and 3 carriers. The frequency of co/super infection of hepatitis D was found to be highest in HBV cirrhosis patients compared to patients having chronic liver disease [non-cirrhotics] and carriers

Comparative study between intranasal antrostomy and antral lavage

This study was conducted to carry out comparison between intranasal antrostomy and antral lavage and comparison of gross appearance of sinus mucosa and any pus/secretion during operation and pre-operative radiological findings. To establish the following facts: i] Improve the aeration and draining of maxillary sinus to prevent the complications of maxillary sinusitis. ii] Gross appearance of sinus mucosa and any pus/secretion in patients not responding to conservative management, Prospective study. This study was conduded in the departments of ENT, Chandka Medical College Hospital, Larkana and Civil Hospital, Karachi from Dec 2004 to Dec 2007. Total no of 150 cases were selected in this study with non febrile, acute, sub-acute and chronic maxillary sinusitis, divided into two groups. First group was treated with antral lavage under general anaesthesia. The second group was treated by intra nasal antrostomy under general anaesthesia. The comparison data between 1st and 2nd and between 2nd and 3rd lavage nearly the same with minor degree of improvement. Most of the patients undergoing for intra nasal antrostomy [including 33 patients who were not responding to antral lavage] were relieved from their symptoms by this procedure