Systemic lupus erythematosus following acute lymphocytic Leukemia

Systemic lupus erythematosus [SLE] is a chronic inflammatory disorder of autoimmune origin, characterized by a wide variety of associations and an unpredictable course. The association of SLE and myeloproliferative and lymphoproliferative malignancies is widely reported in the adult literature [1-4]. Most of the data show that the malignancy is detected after the diagnosis and treatment of SLE [4]. However, the development of SLE has been described following treatment of different types of malignancies [5-8]. There is only scarce information available as to the association of both disease conditions in children. We report here a girl with SLE diagnosed 4 years after acute lymphocytic leukemia [ALL] was successfully treated