Serum gamma glutamyl transpeptidase as a tumour marker in patients with non Hodgkin's lymphoma

Levels of gamma glutamyl transpeptidase and lactic dehydrogenase were measured in the serum of 20 patients with advanced clinical stages of non-Hodkin's lymphoma before treatment and after four cycles of combination chemotherapy. Both were found to be significantly elevated in the active disease and they decrease significantly with the achievement of complete clinical remission. No correlations were detected between the serum levels of both enzymes indicating that the mechanisms of the rise of both enzymes may be different. So, serum gamma glutamyl transpeptidase can be used as a tumor marker in non- Hodkin's lymphoma