ABSTRACT
Background: Polycystic ovary syndrome [PCOS] is an endocrinopathic disorder most commonly experienced by women of reproductive age, and it is characterized by a low-grade chronic inflammatory condition. Excessive fat deposit has been long considered as an etiological factor in the pathogenesis of this inflammatory condition. Currently, body mass index [BMI] or percentage of body fat is used as a marker to assess the body fat composition of a person
Objective: To determine whether BMI or body fat percentage [BFP] can be used as a better marker for measuring inflammation related to body fat accumulation in polycystic ovary syndrome patients
Materials and Methods: This study took place at the Center for Reproductive Medicine, Yasmin Clinic, Cipto Mangunkusumo Hospital from January to December 2015. In this cross-sectional study, 32 reproductive age women with PCOS according to the Rotterdam criteria [2003] participated. Women with hyperandrogenism caused by non-classic congenital adrenal hyperplasia, pregnant and lactating women, etc., were excluded. Some variables such as BMI, clinical hyperandrogenism sign, BFP, and inflammatory markers were assessed and statistically analyzed
Results: From a total of 32 subjects of the study, BFP had a significant positive correlation with procalcitonin levels [r=0.35; p=0.048], while BMI did not [r=0.27; p=0.131]
Conclusion: BFP can be used as a better marker for measuring inflammation related to body fat accumulation in PCOS subjects