ABSTRACT
OBJECTIVE: To assess whether a difference exists in coronary heart disease clinical manifestations and the prevalence of risk factors between Japanese immigrants and their descendents in the city of Säo Paulo. METHODS: Retrospective analysis of coronary artery disease clinical manifestations and the prevalence of risk factors, comparing 128 Japanese immigrants (Japanese group) with 304 Japanese descendents (Nisei group). RESULTS: The initial manifestation of the disease was earlier in the Nisei group (mean = 53 years), a difference of 12 years when compared with that in the Japanese group (mean = 65 years) (P<0.001). Myocardial infarction was the first manifestation in both groups (P = 0.83). The following parameters were independently associated with early coronary events: smoking (OR = 2.25; 95 percent CI = 1.35-3.77; P<0.002); Nisei group (OR = 10.22; 95 percent CI = 5.64-18.5; P<0.001); and female sex (OR = 5.04; 95 percent CI = 2.66-9.52; P<0.001). CONCLUSION: The clinical presentation of coronary heart disease in the Japanese and their descendents in the city of Säo Paulo was similar, but coronary heart disease onset occurred approximately 12 years earlier in the Nisei group than in the Japanese group
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Coronary Disease , Age of Onset , Aged, 80 and over , Brazil , Hypercholesterolemia , Hypertriglyceridemia , Japan , Prevalence , Retrospective Studies , Risk FactorsABSTRACT
No presente estudo foi analisado o perfil da doença coronariana em imigrantes de origem japonesa e de seus descendentes na cidade de São Paulo, quantoà apresentação clínica e fatores de risco associados. A manifestação inicial da doença ocorreu mais cedo nos nisseis, e a diferença observada foi de 12 anosquando comparada com os imigrantes japoneses. Houve maior prevalência de hipercolesterolemia e maior média do índice de massa corpórea nasmulheres do grupo nissei...