ABSTRACT
Resumen En los últimos años, la introducción de diversos medicamentos biológicos para el tratamiento de la psoriasis ha aumentado considerablemente el arsenal terapéutico del médico, con lo cual se ha logrado un fuerte impacto positivo en el control de la enfermedad. Con el fin de proveer de las mejores recomendaciones para el uso de estos biológicos en los pacientes afectados de psoriasis, el grupo mexicano de expertos en psoriasis PSOMEX ha formulado recomendaciones para mejorar la comprensión y el posicionamiento terapéutico de este tipo de medicamentos.
Abstract In recent years, the introduction of a series of biological drugs for the treatment of psoriasis has considerably increased the therapeutic armamentarium of doctors, and thus a strongly positive impact on the control of this condition has been achieved. With the purpose to provide the best recommendations for the use of these biological agents in patients with psoriasis, the Mexican group of psoriasis experts, PSOMEX, has developed recommendations in order to improve the understanding and therapeutic positioning of this type of medications.
Subject(s)
Humans , Male , Female , Pregnancy , Psoriasis/therapy , Biological Factors/therapeutic use , Pregnancy Complications/therapy , Societies, Medical , Age Factors , Tumor Necrosis Factor-alpha/antagonists & inhibitors , MexicoABSTRACT
Hypohidrotic ectodermal dysplasia (HED) is a very rare disease characterized by the absence of eccrine glands, dry skin, scanty hair, and dental abnormalities. It is caused by mutations within the ED1 gene, which encodes a protein, ectodysplasin-A (EDA). Clinical characteristic are frontal bossing, saddle nose, pointed chin, a prominent supraorbital ridge with periorbital hyperpigmenta-tion, and anodontia. Those affected show great intolerance to heat. We report the first Mexican 2-year-old boy with an Ala349Thr missense mutation from Tamaulipas, México.
Subject(s)
Child, Preschool , Humans , Male , Ectodermal Dysplasia 1, Anhidrotic/genetics , Ectodysplasins/genetics , Mutation, Missense/genetics , Ectodermal Dysplasia 1, Anhidrotic/pathologyABSTRACT
La coccidioidomicosis es una micosis profunda causada por el hongo Coccidioides immitis. Las formas clínicas de presentación más comunes son la pulmonar y la cutánea en ésta, han sido descritos varios tipos: polimorfa, verrugosa, ulcerativa, queloidea, colicuativa y esporotricoide. Se mencionan dos casos poco comúnes tratados exitosamente con fluconazol y uno con intraconazol