Mania with Aarskog-Scott Syndrome.

Aarskog-Scott syndrome is transmitted as an X-linked trait and affects males. We report a 10-year-old boy presenting with complaints of increased temper tantrums, demanding behavior, grandiose ideas, overfamiliarity, abusive assaultive behavior and tobacco abuse. On examination, patient had most of the physical characteristics of Aarskog-Scott Syndrome. He also had global developmental delay and attention deficit hyperactivity disorder. This is the first case report of Aarskog Scott syndrome combined with mania.

Prevalence of oral mucosal lesions and variations in Indian public school children

Aim: To study the nature and distribution of oral mucosal lesions and variations in children.Methods: This investigation was a cross-sectional study. All the study subjects were taken fromgovernment primary school. Children were in the age group of 4-14years. The children whowere attending the Department of Pediatric Dentistry for dental check up were examined. Results:A total of 1,003 children were included in the present study,. The mucosal lesions were observedin 643 (64.11%) children, developmental variations of mucosa were evident in 220 (21.93%)children and normal mucosal variations were present in 391 (38.98%) children. The mostcommonly observed mucosal lesions were gingivitis, gingival abscess and traumatic ulcers. Themost frequent developmental mucosal variations were ankyloglossia and high frenal attachment.Normal mucosal variations noted were linea alba buccalis and fordyce’s spots. Distribution ofmucosal lesions/variations were same among both the gender except fordyce’s spots (p=0.018).Parotid papillae and pigmented spots had positive relation with age. Conclusions: Mucosallesions/variations were present in more than half of the children in this study. Only few oralmucosal lesions had gender differences and vary with age.

Burkitt's lymphoma in an Indian girl: a case report.

Burkitt's lymphoma (BL) is a rare monoclonal proliferation of B-lymphocytes and is classified as a poorly differentiated lymphocytic lymphoma. This tumor was first noted in Africans. The cause of this tumor is debatable, but strong evidence implicates Epstein-Barr virus in its development. This tumor predominantly affects children and is probably the fastest growing tumor in humans, with exuberant proliferation. It is a very rare malignancy accounting for only 0.76% of solid malignant tumors among Indian children. A case of BL of the mandible in a 9-year-old girl of Indian origin is reported.

Malignant peripheral nerve sheath tumour: an elusive diagnosis.

Malignant peripheral nerve sheath tumour (MPNST) also termed as spindle cell malignancy of the peripheral nerve Schwann cells or neurogenic sarcoma, represents approximately 10% of all soft tissue sarcomas. This tumour is usually found in the lower extremities and only 10-12% of all lesions occur in the head and neck region, which makes it a rare entity. The diagnosis of MPNST has been described as one of the most difficult and elusive diagnosis in the soft tissue diseases because of its non-specific presentation both clinically and histopathologically. This was overcome by the use of immunohistochemistry. A case of MPNST of the left maxillary antrum in a 45 -year -old male patient is reported.

Extragingival pyogenic granuloma.

Pyogenic granuloma is a well-known localized granulation tissue overgrowth in reaction to mild irritation. Although it is known to show a striking predilection for the gingiva, it can be found extragingivally with varying clinical features that sometimes may mimic more serious lesions such as malignancies. The clinical diagnosis of such an uncommon extragingival pyogenic granulomra can be quite challenging. The purpose of this article is to report an unusual case of extragingival pyogenic granuloma occurring on the lower lip, which presented as a cutaneous horn.