Argyrophilic proteins of the nucleolar organizer region in bladder tumors

The introduction of a simple one - stage silver staining technique that identifies nucleolar organizer regions - associated proteins has been adapted and applied to paraffin sections, and used to examine changes in nucleolar organizer region numbers in a variety of benign and malignant conditions. In the current study Argyrophilic proteins of NOR's were studied in 32 Consecutive patients wit bladder tumor, while there is a statistical separation between normal, inflammatory, dysplastic and neoplastic urothelium

Fine needle aspiration cytology versus histopathology in diagnosing lymph node lesions

Fine needle aspirates [FNA] of superficial lymph nodes were obtained from 150 patients complaining of lymphadenopathy. Cytological findings were analysed in correlation with the corresponding histopathological diagnosis of the same excised nodes. Benign lesions were found in more than half of the patients [55.3%], the majority of which were nonspecific reactive hyperplasia followed by tuberculous lymphadenitis. Lymphomas constituted the main pathology in malignant involvement [26.0%], while metastatic lesions formed 16.7% and leukaemia 2.0%. The results of FNA compared favourably with those of tissue biopsies, with an accuracy rate of 89.6% for malignant lymphadenopathy. The appropriate use of FNA may obviate the need for an open biopsy

Lymphadenopathy: a histopathologic study of 1145 biopsies

In a retrospective study, 1145 lymph node biopsies of patients with lymphadenopathy were examined histologically in Saddam's Medical City Teaching Hospital Laboratoties from 1986-1990. Granulomatous lymphadenitis of tuberculous origin is still a common cause of lymphadenpathy [16.1%], only preceeded by the group of inflammatory/reactive diseases which constituted 31.5%. Primary malignant lymphomas both Hodgkin's disease and Malignant Non- Hodgkin's Lymphoma were detected in 22% of the total with nearly equal incidence [10.9% and 11.1%] respectively. Although the study excluded regional lymph nodes that were attached to surgical specimens of resected malignant tumors, the incidence of metastatic malignancies presented as lyrnphadenopathy were still high and constituted 20.3%. Our results were consistent with similar Iraqi studies