ABSTRACT
Dengue fever is a major infection in the world which geographically expanded. The disease is caused by dengue virus that transfers by Aedes mosquito mainly Ae. aegypti. It is endemic in Saudi Arabia and several outbreaks were reported. The virus primary affects different age groups. Dengue virus can cause classic dengue fever, dengue hemorrhagic fever and dengue shock syndrome. This study reviewed the clinical pictures, laboratory results and outcome of
DF in adults and pediatrics. The retrospective descriptive study included 274 DF patients was conducted at Andalusia Hospital, Jeddah, Saudi Arabia over one year. Demographic data, clinical spectrum and laboratory investigations were recorded. The results showed that pediatrics were 45/274 [16.4%], while adults were 229 [83.6%], males were more dominant than females [30 or 66.7% and 169 or 73.8%] in pediatrics and adults respectively. Headache myalgia, and retro-orbital pain were the main clinical pictures in adults [p<0.05], while vomiting and diarrhea were prevalent in pediatrics [p<0.05]. Anemia, thrombocytopenia and elevated liver enzymes were significantly higher in adults than pediatrics [p<0.05]. Hospital stay and severe DF [DHF and DSS] were significantly higher in adults than pediatrics [p<0.05]
ABSTRACT
The aim of the study was to perform a comparative study between dipyridamole Technetium Tc-99m sestamibi single photon emission computed tomographic scintigraphy [DMIBI] and dobutamine-atropine stress echocardiography [DASE] in assessment of coronary artery disease [CAD] in correlation to the coronary angiography. The study included 62 patients 43 males and 19 females [mean age: 60 +/- 11 years]. All patients underwent multistage DASE, DMIBI and coronary angiography over one month's time. These procedures were performed according to standard techniques and analysed in comparative issue for the sensitivity and their specificity in assessment of CAD. The study revealed 10 patients with three-vessel disease, 11 patients with 2 and 20 patients with single vessel disease. The other 21 patients had insignificant coronary disease for intervention. DASE and DMIBI were similarly sensitive [87% and 80% respectively] for the detection of CAD. However. DASE was more specific [91% vs. 73%, p<0.01]. Detection of Multiple wall motion abnormalities and perfusion defects were similar in both tests [72% vs. 66% respectively]. However, DASE was more specific than DMIBI [95% vs. 76% respectively p<0.01]. DASE and DMIBI were moderately concordant for the detection and extent of CAD [p<0.0001] but fairly concordant [p<0.001] in the detection of type abnormalities [normal, fixed, ischaemic or mixed]. DASE and DMIBI were comparable tests for the detection of CAD. Both were sensitive for the detection of CAD and moderately sensitive for the detection of the extent of the disease. However, DASE was more specific than DMIBI particularly in multi-vessels disease