ABSTRACT
A total number of 42 ewes [local breed], 2-5 years old, was selected from a flock containing 250 heads and used in this study. The animals were grazed in free pasture at El-Tall El-Kebir region, Ismailia Governorate. The pastures were improved using azotic urea and lime superphosphate as fertilizers. After the clinical and parasitological examination of the blood, feces and skin, the ewes were divided into two groups [20 healthy controls, group A, and 22 hypocupremic ewes manifested by alopecia and wool abnormalities, group B]. It was concluded that the biochemical analysis of the biological samples of sheep is a reliable tool for the early diagnosis of some nutritional deficiency disorders and cupric glycinate is an effective treatment for hypocupremic sheep