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1.
Journal of Ophthalmic and Vision Research. 2009; 4 (4): 266-269
in English | IMEMR | ID: emr-100032

ABSTRACT

Several techniques have been employed for repositioning dislocated intraocular lenses [lOLs]. Herein, we describe a simplified and modified technique in which scleral fixation is performed together with temporary externalization of IOL haptics through a small, superior clear corneal incision. The sutures are tied to the externalized haptics; the haptics are then repositioned into the anterior chamber followed by IOL reim-plantation into the ciliary sulcus. Using this technique, the dislocated IOL is repositioned under direct visualization without need for IOL extraction or extensive intraocular manipulations


Subject(s)
Cataract Extraction , Fixation, Ocular , Lenses, Intraocular
2.
Journal of Ophthalmic and Vision Research. 2008; 3 (2): 102-107
in English | IMEMR | ID: emr-143557

ABSTRACT

To compare the efficacy and safety of 1.25 mg versus 2.5 mg intravitreal bevacizumab [IVB] for treatment of choroidal neovascularization [CNV] associated with age-related macular degeneration [AMD]. In this randomized clinical trial, consecutive patients with active CNV associated with AMD received 1.25 mg or 2.5 mg IVB. Best corrected visual acuity [BCVA], foveal thickness and side effects of therapy were evaluated one and three months after intervention. Overall 86 subjects were enrolled and completed the scheduled follow-up. Forty seven and 39 patients received 1.25 and 2.5 mg IVB respectively. The study groups were balanced in terms of baseline characteristics such as age, BCVA and foveal thickness. Mean improvement in BCVA was 0.06 +/- 0.3 logMAR in the 1.25 mg group and 0.07 +/- 0.34 logMAR in the 2.5 mg group [P=0.9]. Mean decrease in foveal thickness was 49 +/- 36 micro m in the 1.25 mg group and 65 +/- 31micro m in the 2.5 mg group [P=0.6]. Three cases of vitreous reaction and one case of massive subretinal hemorrhage were observed in the 2.5 mg group. Double dose [2.5 mg] IVB does not seem to be more effective than regular dose [1.25 mg] injections for treatment of CNV due to AMD and may lead to more complications


Subject(s)
Humans , Male , Female , Antibodies, Monoclonal/administration & dosage , Macular Degeneration/drug therapy , Angiogenesis Inhibitors , Vascular Endothelial Growth Factor A , Treatment Outcome , Prospective Studies , Aged , Visual Acuity
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