ABSTRACT
Recent clinical studies comparing bupivacaine 0.25% and ropivacaine 0.25% reported comparable analgesia and motor block during labaur. An opioid is combined with the local anesthetic to reduce the incidence of side effect and to improve analgesia for the relief of labour pain. Aim of our study was to evaluate the effects of epidural bupivacaine 0.25% compared with ropivacaine 0.25% both combined with sufentanyl for the initiation and maintenance of analgesia during delivery and labour
Subject(s)
Humans , Female , Analgesia, Epidural , Bupivacaine , Sufentanil , Drug Therapy, CombinationABSTRACT
Sixty children undergoing day-case tonsillectomy were randomly allocated to receive anatomic tonsillar infiltration at multiple level with I/ml tonsil of warmed lidocaine 2% to which was added either 1 ml 0.9% saline [lidocaine group] or 1 ml 8.4% sodium bicarbonate [alkaline group]. Pain and behavior were assessed Broadman E.M., et al.; 1989 and Bissonnette B. 1990 and Conventry D. M. 1989 and 12 hours postoperatively. The assessments were double blind and performed by the same observer. No significant differences in post-operative pain or in analgesic consumption were found between the two groups at any time. Patients were more likely to have lower pain scores during the first 12 hours post-operatively if they received alkalinised lidocaine. There were significantly [P<0.05] more patients awake and calm at 2 and 4 hours post-operatively in the alkaline group. Alkalinisation of lidocaine for peritonsillar infiltration appears to confer some benefit to our standard Peri-operative analgesic regimen