ABSTRACT
Background: The77% of all non-communicable illnesses (NCDs) deaths are in low-and middle-income countries. Cardiovascular diseases account for most NCD deaths, or 17.9 million people annually, followed by cancers (9.3 million), respiratory diseases (4.1 million), and diabetes (1.5 million). These 4 groups of diseases account for over 80% of all premature NCD deaths. Objective was to study prevalence of NCDs and its trends with respect to age and gender. Methods: The present community based descriptive observational studywas conducted at Navodaya medical college hospital and research centre, Raichurthatcaters Urban and ruralareaof Raichur. The 4063 apparently healthy population from urban and rural part of Raichur were screened during the multi diagnostic mega camp at urban and rural areas around Raichur during the period of January to September 2021. Results:Prevalence of diabetes in our study was 46.3%, hypertension 45.3%, cataract 46.3% and COPD as 20.7%. Prevalence of diabetes was more in 41-60 years i.e., 41.6%. Prevalence of hypertension was more in 41-50 years i.e., 25.3%. Prevalence of diabetes was more in males i.e., 54.1%. Prevalence of hypertension was more in males i.e., 50.8%. Conclusions: Prevalence of all NCDs was more in above 40 years and more in males except COPD.
ABSTRACT
Background: Obesity and overweight is increasing nowadays among the medical students. Erratic eating habits and other lifestyle related risk factors are mainly implicated for this increasing burden, and research related to these risk factors is essential, considering their role as future physicians and role models in public health intervention programs. The present study was conducted to estimate the BMI values of medical students and to compare obesity among male and female students with their socio-demographic factors, eating habits and lifestyle.Methods: A cross-sectional study was conducted among medical students in a medical college in Kerala during 1st May 2018 to 30th July 2018. A total of 573 students out of 600 participated in the study. Using a structured questionnaire data was collected. BMI was calculated for 483 medical students with age group of 20 years and above including 173 males and 310 females. SPSS version 17 was used for statistical analysis.Results: Using WHO BMI classification 18.2% were overweight and 2.1% were obese. Using Asia- Pacific BMI classification 18.2% were overweight and 20.3% were obese. Male students were more obese than females. Skipping breakfast, eating full stomach, not knowing balanced nutrition, eating fatty foods and snacks, eating more under stress and drinking soft drinks were common unhealthy eating habits among obese students.Conclusions: Obesity and overweight is very prevalent among medical students. Improving their knowledge regarding balanced nutrition, regular eating habits, proper stress management and adoption of healthy lifestyle will result in proper body weight and prevent obesity complications.
ABSTRACT
Background: The Incidence of Cerebral Venous Thrombosis (CVT) is around 3-4 cases among one million population affecting children and young adults. In India the puerperal CVT is 10-12 times more common than western countries. Even though there is apparent “rarity” of the condition but advances in knowledge and available investigation in terms of imaging (CT scan/MRI) diagnosis can be done early for appropriate treatment and decreasing the morbidity and mortality.Methods: A prospective study was conducted at Karnataka Institute of Medical Sciences, Hubli, Karnataka from December 2014 to November 2015. A total of 36 patients were included in the study.Results: Mean age of females in the study was 27.06±9.033years. 75% had seizures, 47.2% had headache, 19.4% had focal neurological deficit, 13.9% had altered sensorium, 8.3% had cranial nerve deficits 5.6% had speech deficits. 72.22% of patients and were in peripartum period and 27.8% were non-pregnant. 72.2% had superior sagittal sinus involvement, 47.2% had transverse sinus, 47.2% had sigmoid sinus, and 13.9% had internal jugular vein and 5.6% straight sinus. 47.2% had single sinus involvement, and 52.8% had multiple sinus involvement. 94.4% patients were managed conservatively and 5.6% were managed by neurosurgical intervention. 94.4% patients survived and 5.6% had mortality.Conclusions: Cerebral venous sinus thrombosis is most common in young females during peripartum period. Early diagnosis, treatment and if necessary neurosurgical intervention has good outcome.
ABSTRACT
Background: Fixed Dose Combinations (FDCs) are defined by the World Health Organization (WHO) as combination of two or more active ingredients in a fixed ratio of doses. According to the FDA, “two or more drugs may be combined in a single dose when each component makes a contribution to the claimed effects, and the dosage of each component (i.e., amount, frequency, and duration) is such that the combination is safe and effective for significant patient population requiring such concurrent therapy. However, certain disadvantages like incompatible pharmacokinetics, inflexible dose ratio, increased toxicity and cost, contraindication of one component of the FDC decreased their utility. Adverse effect of any one component also limits their use. The aim of the study is to compare and evaluate the knowledge, attitude and practices about prescribing fixed dose combinations among junior resident doctors (JRs) and interns (INTs) at SDM College of Medical Sciences and Hospital Dharwad.Methods: A cross-sectional study was carried out in 134 doctors using pre-validated 10 item questionnaire with details of participant’s information followed by questions regarding knowledge, attitude and prescribing practice of fixed dose combinations was used as a tool, administrated to all the resident doctors and the collected data was analysed.Results: Our study revealed that knowledge about FDCs was lacking in JRs and INTs. They were not able to point out the actual advantages and disadvantages of FDCs. Knowledge about rational/irrational, banned FDCs and availability of WHO EML was also lacking.Conclusions: There is need to improve knowledge about rationality, essential medicine list, usage and banned FDCs in undergraduate medical students to promote the rational use of drugs.
ABSTRACT
Isolated duodenal injury following blunt abdominal trauma (BAT) is relatively rare. The incidence of duodenal injuries is 11.2-26% due to blunt trauma. The choice of treatment must be tailored to the nature of the defect and the amount of tissue lost. We present a series of three cases of duodenal injury due to trivial trauma of which two cases of duodenal perforation were treated surgically and one was a duodenal hematoma managed conservatively. Varieties of surgical techniques have been described for the management of patients with duodenal injuries. The surgeon should select the most appropriate procedure based on the type and conditions of the duodenal injury. CECTscan of abdomen remains valuable tool in children with BATfor diagnosis and further management.
ABSTRACT
Background: Polycystic ovarian syndrome (PCOS) is the multisystemic disorder and most common reproductive endocrinopathy of women during their childbearing years, expressed in wide varieties of clinical signs and symptoms. It is characterized by a varied and often complex array of metabolic and endocrine abnormalities, including hyperinsulinaemia, hyperglycaemia, glucose intolerance and obesity which put women with PCOS at a higher risk for diabetes, hypertension, dyslipidemia, and cardiovascular disease. Objectives: To estimate Fasting blood glucose and lipid profile in women with PCOS and normal females. Materials and Methods: After Ethical Committee Approval, blood samples were collected from 50 diagnosed PCOS cases and 50 healthy controls (premenopausal women); aged 18 to 40 years. Fasting plasma glucose and lipid profile were investigated in both PCOS patients and controls. The correlation between these biochemical parameters were then studied in the PCOS group. Data analysis done using studentʽ t’ test. Results: There was a significant increase in fasting plasma glucose levels in PCOS patients as compared to controls. PCOS women had higher BMI with increased total cholesterol, TGL, LDL-C, VLDL-C and lower HDL-C (P < 0.05) as compared to the controls which was statistically significant. The levels of glucose showed significant positive correlation with total cholesterol(P<0.01), triglycerides(P<0.05), LDL-C (P<0.01) whereas non-significant negative correlation with HDL-C. Conclusion: The findings of this study confirms the association between Glucose, BMI and dyslipidaemia in PCOS and may help to identify women with PCOS at risk of cardio metabolic syndrome thereby confirming the association between PCOS and cardiovascular risk factors.
ABSTRACT
Aim: To estimate prevalence of TB among inmates and staff of three prisons in south India. Place of Study: The study was undertaken in three purposively selected prisons in Karnataka State, India, namely, Belgaum, Mysore and Mangalore prisons. Methodology: A descriptive, cross-sectional study was undertaken among a total of 2450 inmates and 280 staff at the three selected prisons. Inmates and prison staff were screened for cough of ≥ 2 weeks and the identified TB suspects were subjected to sputum microscopy for acid fast bacilli using ZN staining and fluorescent microscopy. Results: 81 TB suspects were identified among the inmates and none among the staff. Of the 81 TB suspects, none were positive for acid fast bacilli. 10 inmates at the prisons were already on DOTS for pulmonary TB. A prevalence of pulmonary TB of 4/1000 prison inmates was estimated. Unmet need for medical care was elicited among TB suspects. Past history of anti-TB treatment and history of current smoking were identified as significant risk factors for TB in the selected prisons. Conclusion: The estimated prevalence of pulmonary TB in the selected prisons (4/1000 prison inmates and staff) was almost twice that in the Indian general population (2.11/1000 general population).
ABSTRACT
Introduction: Non-alcoholic fatty liver disease (NAFLD) is a condition characterized by excess accumulation of fat in the liver occurring in people who consume little or no alcohol. This study was aimed at estimating the prevalence of fatty liver in type 2 diabetic patients using ultrasonography and to also to study the correlation between coronary risk factors, coronary artery disease and fatty liver. Materials and methods: This was a cross-sectional study conducted on 150 patients above the age group of 30yrs who were already diagnosed of type 2 diabetes mellitus and on treatment for T2DM were recruited according to inclusion criteria Results: In the present study it was observed that 54 % of the diabetic patients had fatty liver and 46 % had no fatty liver disease on ultrasonography. Out of the 81 diabetic patients who had fatty liver, grade I fatty liver or mild steatosis was observed in 69.1 % cases while 44.9% of cases with no fatty liver disease and 49.4% of cases with non-alcoholic fatty liver disease and were in the age group of 51- 60 yrs with male predilection. 88 patients out of 150 were hypertensive, in patients with no fatty liver disease 59.4 % patients presented with hypertension and 58% hypertensive patients with nonalcoholic fatty liver disease. Mean BMI, waist circumference, HBA1c and liver enzymes (AST and ALT) were significantly higher in patients with fatty liver than in patients without fatty liver. The mean total cholesterol levels (178.18), the mean triglyceride levels (154.9) and mean LDL cholesterol (103.8) were significantly higher in patients with fatty liver when compared to those without fatty liver. Mean HDL cholesterol in patients with fatty liver was 43.3 which were significantly lower than Ramulu Pulimaddi, Amruth Rao Parveda, Dhanunjaya Dasari. Prevalence of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetic patients in correlation with coronary artery disease. IAIM, 2016; 3(11): 118-128. Page 119 mean HDL cholesterol of 46.21 in patients without fatty liver. The prevalence of metabolic syndrome (66.7%) and CAD (59.3%) were significantly higher in the NAFLD subgroup. Conclusion: The prevalence of NAFLD in type 2 diabetics is very high. NAFLD is associated with higher prevalence of metabolic syndrome and coronary artery disease. There is clustering of traditional coronary risk factors in patients with NAFLD.