ABSTRACT
Medicinal plants are unique in having the ability to produce diverse chemical compounds with remarkable biologicalactivities. Investigations of medicinal plants resulted in the discovery of a large number of bioactive compoundswith excellent therapeutic properties. Solanum surattense, a perennial wild growing medicinal herb, is widely usedin the traditional medicine. Exhaustive literature availability reveals the presence of phytochemical compounds fromdifferent plant parts like roots, stem, leaves, fruits, and seeds reported to possess a wide range of pharmacologicalactivities like hepatoprotective, cardioprotective, antiasthmatic and mosquito repellents properties. Intensiveinvestigation on phytochemical constituents resulted in isolation of alkaloid and steroidal compounds solasonoine,solamargine, campesterol, and diosgenin. Evaluation of therapeutic activity of isolated compounds proved as potentones with reference to the standard. Current literature on the pharmacological activity of S. surattense confirms thescientific validation of folklore claims and its traditional use to cure various ailments. Present review is undertaken tosummarize all the available information on pharmacological activities, which provide a baseline support for furtherexploration of its unexplored therapeutic effects like immunomodulation, antipiles activity, antianaphylactic activity,and sexual behavior claimed by folklore.
ABSTRACT
Medicinal plants are unique in having the ability to produce diverse chemical compounds with remarkable biologicalactivities. Investigations of medicinal plants resulted in the discovery of a large number of bioactive compoundswith excellent therapeutic properties. Solanum surattense, a perennial wild growing medicinal herb, is widely usedin the traditional medicine. Exhaustive literature availability reveals the presence of phytochemical compounds fromdifferent plant parts like roots, stem, leaves, fruits, and seeds reported to possess a wide range of pharmacologicalactivities like hepatoprotective, cardioprotective, antiasthmatic and mosquito repellents properties. Intensiveinvestigation on phytochemical constituents resulted in isolation of alkaloid and steroidal compounds solasonoine,solamargine, campesterol, and diosgenin. Evaluation of therapeutic activity of isolated compounds proved as potentones with reference to the standard. Current literature on the pharmacological activity of S. surattense confirms thescientific validation of folklore claims and its traditional use to cure various ailments. Present review is undertaken tosummarize all the available information on pharmacological activities, which provide a baseline support for furtherexploration of its unexplored therapeutic effects like immunomodulation, antipiles activity, antianaphylactic activity,and sexual behavior claimed by folklore.